FOXA1 antibody | FOXA1/1512
Mouse anti Human FOXA1 antibody recognizes FOXA1, also known as Hepatocyte nuclear factor 3-alpha, HNF-3-alpha, HNF-3A, TCF-3A or transcription factor 3A.
FOXA1 encodes a member of the forkhead class of DNA-binding proteins.
FOXA1 encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver (provided by RefSeq, Jul 2008).
Mouse anti Human FOXA1 antibody detects a band of 50 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
FOXA1 encodes a member of the forkhead class of DNA-binding proteins.
FOXA1 encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver (provided by RefSeq, Jul 2008).
Mouse anti Human FOXA1 antibody detects a band of 50 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Mouse anti FOXA1 antibody detects a band of approximately 50 kDa in HepG2 cell lysates
- Product Form
- Purified IgG - liquid
- Preparation
- Mouse monoclonal antibody purified by affinity chromatograpy on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- Recombinant human FOXA1 (aa 467-614)
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P55317
- Entrez Gene
- FOXA1
- GO Terms
- GO:0003690 double-stranded DNA binding
- GO:0003704 specific RNA polymerase II transcription factor activity
- GO:0003705 sequence-specific enhancer binding RNA polymerase II transcription factor activity
- GO:0005667 transcription factor complex
- GO:0006338 chromatin remodeling
- GO:0009790 embryo development
- GO:0007389 pattern specification process
- GO:0008134 transcription factor binding
- GO:0008301 DNA bending activity
- GO:0008634 negative regulation of survival gene product expression
- GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
- GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
- GO:0010843 promoter binding
- GO:0016563 transcription activator activity
- GO:0016566 specific transcriptional repressor activity
- GO:0019904 protein domain specific binding
- GO:0032355 response to estradiol stimulus
- GO:0033148 positive regulation of estrogen receptor signaling pathway
- GO:0042593 glucose homeostasis
- GO:0045666 positive regulation of neuron differentiation
- GO:0045931 positive regulation of mitotic cell cycle
- GO:0048665 neuron fate specification
- GO:0051091 positive regulation of transcription factor activity
- GO:0060441 epithelial tube branching involved in lung morphogenesis
- GO:0060487 lung epithelial cell differentiation
- GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
- GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development
- GO:0060740 prostate gland epithelium morphogenesis
- GO:0060741 prostate gland stromal morphogenesis
- GO:0060743 epithelial cell maturation involved in prostate gland development
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of FOXA1 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
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