CD75s antibody | LN-1

100% Secure

Mouse anti Human CD75s

Product Type
Monoclonal Antibody
Clone
LN-1
Isotype
IgM
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
MCA1481G C F P* 0.1 mg
Mouse anti Human CD75s antibody, clone LN-1 recognizes the human CD75s cell surface antigen, an alpha2,6 - sialylated carbohydrate epitope expressed by mature B cells (especially germinal centre B cells), red blood cells and some epithelial cells.

Product Details

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Pig
Mink
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgM - liquid
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.05%Sodium Azide
Immunogen
Human lymphocytes and SU-DHL4 cell line.
Approx. Protein Concentrations
IgM concentration 0.1mg/ml

Storage Information

Storage
Store at +4oC or at -20oC if preferred.

This product should be stored undiluted.

Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
Please see label for expiry date.

More Information

UniProt
P15907 Related reagents
Entrez Gene
ST6GAL1 Related reagents
GO Terms
GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity
GO:0005576 extracellular region
GO:0006959 humoral immune response
GO:0018279 protein N-linked glycosylation via asparagine
GO:0030173 integral to Golgi membrane
GO:0032580 Golgi cisterna membrane
GO:0043687 post-translational protein modification
Regulatory
For research purposes only

Applications of CD75s antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Flow Cytometry
Immunohistology - Frozen 1/10 1/100
Immunohistology - Paraffin 1
  1. 1This product requires protein digestion pre-treatment of paraffin sections e.g. trypsin or pronase.
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.

Histology Positive Control Tissue
Human Tonsil

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Human anti Mouse IgM:FITC HCA040F 0.1 mg F
Human anti Mouse IgM:HRP HCA040P 0.1 mg E
Goat anti Mouse IgM:Alk. Phos.(Human Adsorbed) STAR138A 1 ml C E P WB
Goat anti Mouse IgM:RPE STAR86PE 0.5 ml F
Goat anti Mouse IgG/A/M:Alk. Phos. STAR87A 1 mg C E WB
Goat anti Mouse IgG/A/M:HRP (Human Adsorbed) STAR87P 1 mg E

Negative Isotype Controls Available

Description Product Code Pack Size Applications List Price Quantity
Mouse IgM Negative Control MCA692 100 Tests F

Product Specific References

References for CD75s antibody

  1. Epstein, A.L. et al. (1984) Two new monoclonal antibodies (LN-1, LN-2) reactive in B5 formalin-fixed, paraffin-embedded tissues with follicular center and mantle zone human B lymphocytes and derived tumors.
    J Immunol. 133 (2): 1028-36.
  2. Tanimoto, T. & Ohtsuki,Y. (1996) Evaluation of antibodies reactive with porcine lymphocytes and lymphoma cells in formalin-fixed, paraffin-embedded, antigen-retrieved tissue sections.
    Am J Vet Res. 57 (6): 853-9.
  3. Schwartz-Albiez, R. (2002) Carbohydrate and lectin: sections report in Leucoyte Typing VII: white cell differentiation antigens.
    Edited by Mason, D. et al. Oxford University Press. PP149-164.
  4. Aasted, B. et al. (2007) Reactivity of monoclonal antibodies to human CD antigens with cells from mink.
    Vet Immunol Immunopathol. 119: 27-37.

Further Reading

  1. Piriou-Guzylack, L. (2008) Membrane markers of the immune cells in swine: an update.
    Vet Res. 39: 54.