Macrophages/Monocytes antibody | MR-1
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Mouse anti Guinea Pig Macrophages
- Product Type
- Monoclonal Antibody
- Clone
- MR-1
- Isotype
- IgG1
- Specificity
- Macrophages/Monocytes
Antibody Quality and 
Unrivaled 
| Mouse anti Guinea Pig macrophages / monocytes antibody, clone MR-1 recognizes a cytoplasmic component of guinea pig monocytes and most tissue macrophages. Mouse anti Guinea Pig macrophages / monocytes antibody, clone MR-1 does not recognise cortical macrophages of the thymus or microglial cells of the brain. |
- Target Species
- Guinea Pig
- Product Form
- Tissue Culture Supernatant - liquid
- Preparation
- Tissue Culture Supernatant containing 2% foetal bovine serum.
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3).
- Immunogen
- Guinea Pig lymph node stroma.
- Fusion Partners
- Spleen cells from immunised mice were fused with cells of the mouse Sp2/0 myeloma cell line.
- Regulatory
- For research purposes only.
- Guarantee
- 12 months from date of despatch.
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry 1 |  |
Neat | 1/10 |
| Immunohistology - Frozen | |
1/10 |
- 1 Membrane permeabilization is required for this application. The use of Leucoperm (Product Code BUF09) is recommended for this purpose.
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
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References for Macrophages/Monocytes antibody
-
Kraal, G. et al. (1988) Histochemical identification of guinea-pig macrophages by monoclonal antibody MR-1.
Immunology. 65 (4): 523-8. -
Shang, S. et al. (2011) Activities of TMC207, rifampin, and pyrazinamide against Mycobacterium tuberculosis infection in guinea pigs.
Antimicrob Agents Chemother. 55 (1): 124-31. -
Mateo, M. et al. (2011) VP24 is a molecular determinant of Ebola virus virulence in guinea pigs.
J Infect Dis. 204 Suppl 3: S1011-20. -
Bendig, M.M. et al. (2007) Humanized antibodies against leukocyte adhesion molecule VLA-4
Patent Appl WO 1995019790 A1
- RRID
- AB_322840
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