MHC Class II DQ antibody | CC158
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|Mouse anti Bovine MHC class II DQ antibody, clone CC158 recognises Bovine MHC Class II DQ. MHC Class II molecules are constitutively expressed on antigen presenting cells such as dendritic cells, B lymphocytes, monocytes, macrophages, activated T lymphocytes and may be induced on a range of other cell types by interferon gamma.
The major histocompatibility complex (MHC) is a cluster of genes some of which are important in the immune response to infections. In cattle, this complex is referred to as the bovine leukocyte antigen (BoLA) region. There are 2 major types of MHC class IIa molecules encoded by the BoLA which are DR and DQ each composed of an alpha and beta chain.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Carrier Free
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
- Fusion Partners
- Spleen cells from immunised BALB/c mice were fused with cells of the NS1 mouse myeloma cell line.
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. .
|Description||Product Code||Applications||Pack Size||List Price||Your Price||Quantity|
|Rabbit F(ab')2 anti Mouse IgG:RPE||STAR12A||F||1 ml||Log in|
|List Price||Your Price|
|Description||Rabbit F(ab')2 anti Mouse IgG:RPE|
|Rabbit F(ab')2 anti Mouse IgG:FITC||STAR9B||F||1 mg||Log in|
|List Price||Your Price|
|Description||Rabbit F(ab')2 anti Mouse IgG:FITC|
References for MHC Class II DQ antibody
Stephens, S.A. & Howard, C.J. (2002) Infection and transformation of dendritic cells from bovine afferent lymph by Theileria annulata.
Parasitology. 124 (Pt 5): 485-93.
Yamakawa, Y. et al. (2008) Identification and functional characterization of a bovine orthologue to DC-SIGN.
J Leukoc Biol. 83 (6): 1396-403.
Price,S.J. and Hope, J.C. (2009) Enhanced secretion of interferon-gamma by bovine gammadelta T cells induced by coculture with Mycobacterium bovis-infected dendritic cells: evidence for reciprocal activating signals.
Immunology. 126: 201-8.
Van Rhijn, I. et al. (2007) Massive, sustained gammadelta T cell migration from the bovine skin in vivo.
J Leukoc Biol. 81: 968-73.
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