We offer high quality monoclonal and polyclonal antibodies to a broad range of fertility related biomarkers, including hCG, FSH and LH commonly used for fertility tests and pregnancy-associated plasma protein A (PAPP-A) for prenatal screening.
The hormone human chorionic gonadotropin (better known as hCG) is produced by syncytiotrophoblasts from placenta during pregnancy. Monoclonal anti-hCG antibodies (mostly specific to the beta-unit) are often used in pregnancy tests to measure the blood or urine level of hCG.
hCG can also be used as a tumor marker as its level is elevated in some reproductive organ related cancers, such as seminoma, choriocarcinoma, germ cell tumors, and testicular cancer.
Follicle-stimulating hormone (FSH) and luteinizing hormone (LH) are both produced by gonadotroph cells in the anterior pituitary gland and act synergistically in reproduction. FSH regulates the development, growth, pubertal maturation and reproductive processes, while LH is involved in ovulation and the development of corpus luteum in females and the production of testosterone in males.