Serotonin antibody

Rabbit anti Serotonin

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
Serotonin

Product Code Applications Pack Size List Price Your Price Qty
8250-0004
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Rabbit anti Serotonin antibody recognizes serotonin and stains serotonin containing cells in human ileum and also stains primary and metastatic carcinoid tumours containing serotonin.

Serotonin (also known as 5-hydroxytryptamine or 5-HT) is a biochemical messenger and neurotransmitter synthesized from L-tryptophan. Serotonin has a range of functions, including regulation of gastric motility, and may be related to some psychiatric disorders including schizophrenia and depression.

Target Species
Broad
Product Form
Serum - liquid
Preservative Stabilisers
0.09%Sodium Azide (NaN3)
Immunogen
Synthetic Serotonin, conjugated to bovine Thyroglobulin.
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunofluorescence
Immunohistology - Frozen
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
Histology Positive Control Tissue
Human ileum

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References for Serotonin antibody

  1. Watts, S.W. et al. (2009) Serotonylation of vascular proteins important to contraction.
    PLoS One. 4:e5682.
  2. Abdala-Valencia, H. et al. (2012) Inhibition of allergic inflammation by supplementation with 5-hydroxytryptophan.
    Am J Physiol Lung Cell Mol Physiol. 303: L642-60.
  3. Soveg, F. et al. (2015) Regulation of allergic lung inflammation by endothelial cell transglutaminase 2.
    Am J Physiol Lung Cell Mol Physiol. 309 (6): L573-83.
  4. Kuzay, D. et al. (2022) Effects of thymoquinone in a rat model of reserpine-induced depression
    Brazilian Journal of Pharmaceutical Sciences. 58 e19847.

Immunofluorescence

Western Blotting

Synonyms
5-HT
5-HYDROXYTRYPTAMINE
RRID
AB_2233447
View more products with SEROTONIN specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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