Perforin antibody

Rabbit anti Perforin

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
Perforin

Product Code Applications Pack Size List Price Your Price Qty
AHP2338
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 50 µg loader
List Price Your Price
loader
Search for Batch Specific Datasheets

Rabbit anti perforin antibody recognizes perforin, also known as cytolysin, a cytolytic protein found in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. The importance of perforin in maintaining immune homeostasis and immune surveillance is extremely well documented. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis

Target Species
Rat
Species Cross-Reactivity
Target SpeciesCross Reactivity
Human
Mouse Expected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
30% Glycerol
0.5% Bovine Serum Albumin
0.01% Thiomersal
Immunogen
Synthetic peptide surrounding amino acid 568 of rat perforin
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 0.5 4.0 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti Perforin antibody recognizes a band of approximately 70 kDa in Jurkat lysates

Description Product Code Applications Pack Size List Price Your Price Quantity
Goat anti Rabbit IgG (Fc):Biotin STAR121B E WB 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (Fc):Biotin
Goat anti Rabbit IgG (Fc):FITC STAR121F F 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (Fc):FITC
Goat anti Rabbit IgG (Fc):HRP STAR121P E WB 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (Fc):HRP
Goat anti Rabbit IgG (H/L):HRP STAR124P C E WB 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (H/L):HRP
Sheep anti Rabbit IgG:FITC STAR34B C F 1 mg loader
List Price Your Price
loader
Description Sheep anti Rabbit IgG:FITC
Sheep anti Rabbit IgG:RPE STAR35A F 1 ml loader
List Price Your Price
loader
Description Sheep anti Rabbit IgG:RPE

Synonyms
Cytolysin
UniProt
P35763
Entrez Gene
Prf1
GO Terms
GO:0005886 plasma membrane
GO:0005509 calcium ion binding
GO:0002357 defense response to tumor cell
GO:0002418 immune response to tumor cell
GO:0016021 integral to membrane
GO:0005576 extracellular region
GO:0005829 cytosol
GO:0007623 circadian rhythm
GO:0019835 cytolysis
GO:0022829 wide pore channel activity
GO:0031904 endosome lumen
GO:0051260 protein homooligomerization
GO:0044194 cytolytic granule
GO:0045471 response to ethanol
GO:0051607 defense response to virus
View more products with Perforin specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Rat Products