GRO Beta/MIP-2 antibody
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Rabbit anti Rat GRO Beta/MIP-2
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- GRO Beta/MIP-2
Antibody Quality and 
Unrivaled 
| Rabbit anti Rat GRO beta/MIP-2 antibody recognizes rat GRO beta/MIP-2, also known CXCL2, an 8kD chemokine which promotes neutrophil chemotaxis and degranulation and is expressed by monocytes, fibroblasts, endothelial cells, synovial cell and several tumour cell lines. |
- Target Species
- Rat
- Product Form
- Purified IgG - lyophilized
- Reconstitution
- Reconstitute with 0.1 ml distilled water. The addition of 0.09% sodium azide is recommended for long term storage.
N.B. For functional studies do not add sodium azide. - Antiserum Preparation
- Antisera to rat GRO beta/MIP-2 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present
- Carrier Free
- Yes
- Immunogen
- Recombinant rat GRO beta/MIP-2.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Prior to reconstitution store at -20°C.
After reconstitution store at -20°C.
This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
After reconstitution store at -20°C.
This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
0.5ug/ml | |
| Functional Assays | |
3.0ug/ml | 5.0ug/ml |
| Western Blotting | |
0.1ug/ml | 0.2ug/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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References for GRO Beta/MIP-2 antibody
-
Vallès, A. et al. (2006) Differential regulation of the CXCR2 chemokine network in rat brain trauma: implications forneuroimmune interactions and neuronal survival.
Neurobiol Dis.22: 312-22.
- Synonyms
- CXCL2
- RRID
- AB_2261140
- UniProt
- P30348
- Entrez Gene
- Cxcl2
- GO Terms
- GO:0005615 extracellular space
- GO:0006954 inflammatory response
- GO:0006955 immune response
- GO:0008009 chemokine activity
- GO:0030593 neutrophil chemotaxis
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