Toxoplasma gondii antibody

Rabbit anti Toxoplasma gondii RH Strain

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
Toxoplasma gondii
Region
RH STRAIN

Product Code Applications Pack Size List Price Your Price Qty
9070-0556
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IF 1 ml loader
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Rabbit anti Toxoplasma gondii RH Strain antibody recognizes purified Toxoplasma gondii trophozoites.

T. gondii is an intracellular protozoan parasite that enters its host via the gastrointestinal tract, and is the only member of the Toxoplasma genus. The definitive host of T. gondii is cats, but it can also be carried by a vast number of warm-blooded animals, including humans. Toxoplasmosis is usually minor and self-limiting but can have serious or even fatal effects on a fetus, or if the host is immunocompromised. T. gondii encephalitis (TE) is the most common cerebral opportunistic infection in patients with AIDS.

Target Species
Protozoan
Product Form
Purified IgG - liquid
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.1%Sodium Azide (NaN3)
Immunogen
Toxoplasma gondii RH strain.
Approx. Protein Concentrations
IgG concentration 4.0 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunofluorescence
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

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References for Toxoplasma gondii antibody

  1. Parussini, F. et al. (2012) Intramembrane proteolysis of Toxoplasma apical membrane antigen 1 facilitates host-cell invasion but is dispensable for replication.
    Proc Natl Acad Sci U S A. 109 (19): 7463-8.
  2. Odell, A.V. et al. (2015) Yeast Three-Hybrid Screen Identifies TgBRADIN/GRA24 as a Negative Regulator of Toxoplasma gondii Bradyzoite Differentiation.
    PLoS One. 10 (3): e0120331.
  3. Passeri, E. et al. (2016) Infection and characterization of Toxoplasma gondii in human induced neurons from patients with brain disorders and healthy controls.
    Microbes Infect. 18 (2): 153-8.

RRID
AB_620718