|Rabbit anti Mouse Interleukin-13 antibody recognizes mouse Interleukin-13 (IL-13), a 12.3kDa immunoregulatory cytokine produced primarily by activated T helper type 2 (Th2) cells and also by mast cells and NK cells.
The biological properties of IL-13 include stimulation of B cell proliferation and antibody production. IL-13 plays an important role in the induction of the pathophysiological features of allergic asthma, independently of Immunoglobulin E and eosinophils (Wills-Karp et al. 1998).
- Target Species
- Product Form
- Purified IgG conjugated to Biotin - lyophilized
- Reconstitute with 0.5ml sterile PBS containing 0.1% Bovine Serum Albumin.
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
N.B. For long term storage the addition of 0.09% sodium azide is recommended.
- Antiserum Preparation
- Antisera to mouse IL-13 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present
- Carrier Free
- Recombinant mouse IL-13.
- Approx. Protein Concentrations
- IgG concentration 0.1 mg/ml after reconstitution
- For research purposes only
- 12 months from date of despatch
After reconstitution store at -20°C.
This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
|Application Name||Verified||Min Dilution||Max Dilution|
- AAM34B may be used in a direct ELISA or as the detection reagent in a sandwich ELISA with AAM34 as the capture antibody.
References for IL-13 antibody
Wills-karp, M. et al. (1998) Interleukin-13: central mediator of allergic asthma.
Science. 282 (5397): 2258-61.
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