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Tissue Transglutaminase antibody

Rabbit anti Tissue Transglutaminase

Product Type
PrecisionAb Polyclonal
Polyclonal IgG
Tissue Transglutaminase

Product Code Applications Pack Size List Price Your Price Qty
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 100 µl loader
List Price Your Price

Rabbit anti Human tissue transglutaminase antibody recognizes tissue transglutaminase, also known as protein-glutamine gamma-glutamyltransferase 2, C polypeptide, TG(C), TGase C, TGase H, TGase-2, TGase-H, epididymis secretory protein Li 45, transglutaminase C, transglutaminase H and transglutaminase-2.

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. Encoded by the TGM2 gene, tissue transglutaminase acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. It is also the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for TGM2 (provided by RefSeq, Jul 2008).

Rabbit anti Human tissue transglutaminase antibody detects a band of 78 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Western Blotting
Anti TGM2 detects a band of approximately 78 kDa in K562 cell lysates.
Product Form
Purified IgG - liquid
Rabbit Ig fraction prepared by ammonium sulphate precipitation.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
KLH conjugated synthetic peptide between 429-458 amino acids from the Central region of human tissue transglutaminase
For research purposes only.
12 months from date of despatch.
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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Entrez Gene
GO Terms
GO:0003810 protein-glutamine gamma-glutamyltransferase activity
GO:0046872 metal ion binding
GO:0008415 acyltransferase activity
GO:0043277 apoptotic cell clearance
GO:0045785 positive regulation of cell adhesion



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