Rabbit anti STAT1 (pSer727) antibody
recognizes signal transducer and activator of transcription 1-alpha/beta (STAT1) also known as transcription factor ISGF-3 components p91/p84, when phosphorylated at serine 727. STAT1 is part of the transcription factor STAT family of proteins. STAT proteins form homo- or hetero-dimers once phosphorylated by receptor associated kinases. Following dimerization STAT proteins then translocate to the cell nucleus. Phosphorylation of STAT1 at serine 727 occurs via p38 MAPK (MAPK14) pathways (Ramsauer et al. 2002
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
||Expected from Sequence
||Expected from Sequence
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to STAT1 (pSer727) was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
- Phospho specific-peptide corresponding to residues surrounding serine 727 of human STAT1
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of STAT1 (pSer727) antibody
|Immunohistology - Paraffin
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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Secondary Antibodies Available
Useful Reagents Available
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