RBBP7 antibody

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Anti RBBP7 Antibody (PrecisionAb Polyclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with RBBP7 antibody followed by detection with HRP conjugated Goat anti Rabbit (1/10,000, STAR208P) and visualized on the ChemiDoc MP with 23 second exposure. Arrow points to RBBP7 (molecular weight 52 kDa)

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Rabbit anti RBBP7

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified
Specificity: RBBP7

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VPA00360 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
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Rabbit anti Human RBBP7 antibody recognizes RBBP7, also known as G1/S transition control protein-binding protein RbAp46, histone acetyltransferase type B subunit 2, histone-binding protein RBBP7, nucleosome-remodeling factor subunit RBAP46, retinoblastoma-binding protein 7, retinoblastoma-binding protein RbAp46 and retinoblastoma-binding protein p46.

RBBP7 is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. RBBP7 is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for RBBP7 (provided by RefSeq, Nov 2010).

Rabbit anti Human RBBP7 antibody detects a band of 52 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Anti RBBP7 detects a band of approximately 52 kDa in MOLT-4 cell lysate.
Species Cross-Reactivity: Target Species Cross Reactivity

Mouse

Rat; N.B. Antibody reactivity and working conditions may vary between species.
Product Form: Purified IgG - liquid
Preparation: Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution: Phosphate buffered saline.
Preservative Stabilisers: 0.09% Sodium Azide (NaN₃).
Immunogen: KLH-conjugated synthetic peptide corresponding to aa 1-30 of human RBBP7
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Target Species	Cross Reactivity
Mouse
Rat

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in	Get Quote
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Description	Goat anti Rabbit IgG (H/L):HRP

UniProt: Q16576
Entrez Gene: RBBP7
GO Terms: GO:0006260 DNA replication; GO:0005515 protein binding; GO:0006350 transcription; GO:0007275 multicellular organismal development; GO:0008283 cell proliferation; GO:0016581 NuRD complex; GO:0030308 negative regulation of cell growth; GO:0034080 CenH3-containing nucleosome assembly at centromere; GO:0035098 ESC/E(Z) complex; View More GO Terms; GO:0045449 regulation of transcription; GO:0070370 cellular heat acclimation