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RBBP7 antibody

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Anti RBBP7 Antibody (PrecisionAb Polyclonal Antibody) gallery image 1
Western blot analysis of whole cell lysates probed with RBBP7 antibody followed by detection with HRP conjugated Goat anti Rabbit (1/10,000, STAR208P) and visualized on the ChemiDoc MP with 23 second exposure. Arrow points to RBBP7 (molecular weight 52 kDa)

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Rabbit anti RBBP7

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
RBBP7

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Rabbit anti Human RBBP7 antibody recognizes RBBP7, also known as G1/S transition control protein-binding protein RbAp46, histone acetyltransferase type B subunit 2, histone-binding protein RBBP7, nucleosome-remodeling factor subunit RBAP46, retinoblastoma-binding protein 7, retinoblastoma-binding protein RbAp46 and retinoblastoma-binding protein p46.

RBBP7 is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. RBBP7 is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for RBBP7 (provided by RefSeq, Nov 2010).

Rabbit anti Human RBBP7 antibody detects a band of 52 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. 		PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti RBBP7 detects a band of approximately 52 kDa in MOLT-4 cell lysate
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
KLH-conjugated synthetic peptide corresponding to aa 1-30 of human RBBP7
Regulatory
For research purposes only
Guarantee
12 months from date of despatch
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20oC, avoiding repeated freeze thaw cycles

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description Product Code Applications Pack Size List Price Your Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P WB 2 ml
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Description Goat anti Rabbit IgG (H/L):HRP

UniProt
Q16576
Entrez Gene
RBBP7
GO Terms
GO:0006260 DNA replication
GO:0005515 protein binding
GO:0006350 transcription
GO:0007275 multicellular organismal development
GO:0008283 cell proliferation
GO:0016581 NuRD complex
GO:0030308 negative regulation of cell growth
GO:0034080 CenH3-containing nucleosome assembly at centromere
GO:0035098 ESC/E(Z) complex
GO:0045449 regulation of transcription
GO:0070370 cellular heat acclimation
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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