PTPN2 antibody

Rabbit anti PTPN2

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
PTPN2

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AHP2517
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Rabbit anti PTPN2 antibody recognizes tyrosine-protein phosphatase non-receptor type 2 (PTPN2) also known as T cell protein-tyrosine phosphatase (TCPTP). PTPN2 belongs to the protein tyrosine phosphatase family and regulates many cellular processes including hematopoiesis, inflammatory response, cell division and glucose homeostasis.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse Expected from Sequence
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to PTPN2 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02% Sodium Azide
50% Glycerol
Immunogen
Recombinant human PTPN2
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 1/50 1/200
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti PTPN2 antibody detects a band of approximately 49 kDa in cell lysates under reducing conditions

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UniProt
P17706
Entrez Gene
PTPN2
GO Terms
GO:0005515 protein binding
GO:0005783 endoplasmic reticulum
GO:0005654 nucleoplasm
GO:0006470 protein dephosphorylation
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0060334 regulation of interferon-gamma-mediated signaling pathway
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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