PPP2R2A antibody

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Rabbit anti PPP2R2A

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Product Code Applications Pack Size List Price Quantity
VPA00328
Datasheet
WB
MSDS
100 µl loader

Rabbit anti Human PPP2R2A antibody recognizes PPP2R2A, also known as protein phosphatase 2 (formerly 2A), regulatory subunit B (PR52) alpha isoform, 55 kDa regulatory subunit B, alpha isoform and serine/threonine-protein phosphatase 2A.

The product of the PPP2R2A gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, which associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. The PPP2R2A gene encodes an alpha isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants have been described (provided by RefSeq, Apr 2010).

Rabbit anti Human PPP2R2A antibody detects a band of 52 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Anti PPP2R2A detects a band of approximately 52 kDa in HeLa cell lysate
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
KLH-conjugated synthetic peptide corresponding to aa 126-160 of human PPP2R2A

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles
Guarantee
12 months from date of despatch

More Information

UniProt
P63151
Entrez Gene
PPP2R2A
GO Terms
GO:0000159 protein phosphatase type 2A complex
GO:0005515 protein binding
GO:0004722 protein serine/threonine phosphatase activity
GO:0007165 signal transduction
GO:0006470 protein dephosphorylation
GO:0008601 protein phosphatase type 2A regulator activity
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory
For research purposes only

Applications of PPP2R2A antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P WB 2 ml