Oncostatin M Receptor antibody

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Rabbit anti Oncostatin M Receptor

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Product Code Applications Pack Size List Price Quantity
VPA00324
Datasheet
WB
SDS
100 µl loader

Rabbit anti Human oncostatin M Receptor antibody recognizes the oncostatin M receptor, also known as OSMRB, PLCA1 and oncostatin-M specific receptor beta subunit.

Encoded by the OSMR gene, the oncostatin M Receptor is a member of the type I cytokine receptor family. This receptor heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in the OSMR gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for OSMR (provided by RefSeq, Dec 2009).

Rabbit anti Human oncostatin M receptor antibody detects a band of 111 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Anti oncostatin M receptor detects a band of approximately 111 kDa in HeLa cell lysate
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
2% Sucrose
Immunogen
Synthetic peptide corresponding to the N-terminal region of human oncostatin M receptor

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles
Guarantee
12 months from date of despatch

More Information

UniProt
Q99650
Entrez Gene
OSMR
GO Terms
GO:0002675 positive regulation of acute inflammatory response
GO:0004924 oncostatin-M receptor activity
GO:0019838 growth factor binding
GO:0005900 oncostatin-M receptor complex
GO:0008283 cell proliferation
GO:0008284 positive regulation of cell proliferation
GO:0034097 response to cytokine stimulus
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory
For research purposes only

Applications of Oncostatin M Receptor antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P WB 2 ml