The NDUFS3 gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in NDUFS3 gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency (provided by RefSeq, Apr 2009).
Rabbit anti Human NDUFS3 antibody detects a band of 26 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
- Target Species
- Western Blotting
- Anti NDUFS3 detects a band of approximately 26 kDa in HEK293 cell lysate
- Species Cross-Reactivity
Target Species Cross Reactivity Mouse Rat
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Rabbit polyclonal antibody purified by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- KLH-conjugated synthetic peptide corresponding to aa 251-284 of human NDUFS3
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles
- 12 months from date of despatch
- Entrez Gene
- GO Terms
- GO:0009055 electron carrier activity
- GO:0005515 protein binding
- GO:0005747 mitochondrial respiratory chain complex I
- GO:0006120 mitochondrial electron transport, NADH to ubiquinone
- GO:0006800 oxygen and reactive oxygen species metabolic process
- GO:0006810 transport
- GO:0006917 induction of apoptosis
- GO:0008137 NADH dehydrogenase (ubiquinone) activity
- GO:0030308 negative regulation of cell growth
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- For research purposes only
Applications of NDUFS3 antibody
|Application Name||Verified||Min Dilution||Max Dilution|
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
Secondary Antibodies Available
|Description||Product Code||Applications||Pack Size||List Price||Quantity|
|Goat anti Rabbit IgG (H/L):HRP||STAR208P||WB||2 ml|