IRAK1 antibody


Product Details
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antisera to human IRAK were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.02% Sodium Azide - Immunogen
- Peptide from C terminus of human IRAK
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P51617
- Entrez Gene
- IRAK1
- GO Terms
- GO:0000187 activation of MAPK activity
- GO:0005515 protein binding
- GO:0001959 regulation of cytokine-mediated signaling pathway
- GO:0002755 MyD88-dependent toll-like receptor signaling pathway
- GO:0002756 MyD88-independent toll-like receptor signaling pathway
- GO:0005829 cytosol
- GO:0004704 NF-kappaB-inducing kinase activity
- GO:0004842 ubiquitin-protein ligase activity
- GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
- GO:0005524 ATP binding
- GO:0006916 anti-apoptosis
- GO:0007250 activation of NF-kappaB-inducing kinase activity
- GO:0007254 JNK cascade
- GO:0008063 Toll signaling pathway
- GO:0010008 endosome membrane
- GO:0016563 transcription activator activity
- GO:0031663 lipopolysaccharide-mediated signaling pathway
- GO:0032088 negative regulation of NF-kappaB transcription factor activity
- GO:0034130 toll-like receptor 1 signaling pathway
- GO:0034134 toll-like receptor 2 signaling pathway
- GO:0034138 toll-like receptor 3 signaling pathway
- GO:0034142 toll-like receptor 4 signaling pathway
- GO:0042803 protein homodimerization activity
- GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade
- GO:0045087 innate immune response
- GO:0045323 interleukin-1 receptor complex
- GO:0046777 protein autophosphorylation
- GO:0046982 protein heterodimerization activity
- GO:0048011 nerve growth factor receptor signaling pathway
- GO:0051092 positive regulation of NF-kappaB transcription factor activity
- GO:0051259 protein oligomerization
- GO:0051403 stress-activated MAPK cascade
- GO:0070498 interleukin-1-mediated signaling pathway
- GO:0070555 response to interleukin-1
- Regulatory
- For research purposes only
Applications of IRAK1 antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Immunohistology - Frozen | |||
Immunoprecipitation | 2-4ug/sample | ||
Western Blotting | 1/1000 | 1/2000 |
Secondary Antibodies Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
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Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
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Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
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Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
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Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
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Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
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Sheep anti Rabbit IgG:DyLight®488 | STAR36D488GA | F IF WB | 0.1 mg | ||
Sheep anti Rabbit IgG:DyLight®680 | STAR36D680GA | F IF WB | 0.1 mg | ||
Sheep anti Rabbit IgG:Dylight®800 | STAR36D800GA | F IF WB | 0.1 mg |
Useful Reagents Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB* | 0.5 ml |
Product Specific References
Further Reading
-
Cao, Z. et al. (1996) IRAK: a kinase associated with the interleukin-1 receptor.
Science. 271 (5252): 1128-31.
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