Inhibin Beta B antibody

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Anti Inhibin Beta B Antibody (PrecisionAb Polyclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with inhibin beta B antibody followed by detection with HRP conjugated Goat anti Rabbit (1/10,000, STAR208P) and visualized on the ChemiDoc MP with 150 second exposure. Arrow points to inhibin beta B (molecular weight 52 kDa)

Rabbit anti Inhibin Beta B

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified
Specificity: Inhibin Beta B

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VPA00277 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
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Rabbit anti Human inhibin beta B antibody recognizes inhibin beta B, also known as INHBB, activin AB beta polypeptide and activin beta-B chain.

The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin regulates gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extra-gonadal tissues may vary several fold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion (provided by RefSeq, Jul 2008).

Rabbit anti Human inhibin beta B antibody detects a band of 52 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Anti inhibin beta B detects a band of approximately 52 kDa in human adipose tissue.
Product Form: Purified IgG - liquid
Preparation: Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution: Phosphate buffered saline.
Preservative Stabilisers: 0.09% Sodium Azide (NaN₃).
Immunogen: KLH-conjugated synthetic peptide corresponding to aa 369-397 of human inhibin beta B
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in	Get Quote
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Description	Goat anti Rabbit IgG (H/L):HRP

UniProt: P09529
Entrez Gene: INHBB
GO Terms: GO:0001541 ovarian follicle development; GO:0006952 defense response; GO:0005576 extracellular region; GO:0005125 cytokine activity; GO:0005179 hormone activity; GO:0040007 growth; GO:0008083 growth factor activity; GO:0009267 cellular response to starvation; GO:0046881 positive regulation of follicle-stimulating hormone secretion; View More GO Terms; GO:0046882 negative regulation of follicle-stimulating hormone secretion; GO:0032869 cellular response to insulin stimulus; GO:0032924 activin receptor signaling pathway; GO:0046789 host cell surface receptor binding; GO:0042803 protein homodimerization activity; GO:0045444 fat cell differentiation; GO:0046676 negative regulation of insulin secretion; GO:0048178 negative regulation of hepatocyte growth factor biosynthetic process; GO:0048471 perinuclear region of cytoplasm; GO:0060279 positive regulation of ovulation