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Inhibin Beta B antibody

Rabbit anti Inhibin Beta B

Product Type
PrecisionAb Polyclonal
Polyclonal IgG
Inhibin Beta B

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Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 100 µl loader
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Rabbit anti Human inhibin beta B antibody recognizes inhibin beta B, also known as INHBB, activin AB beta polypeptide and activin beta-B chain.

The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin regulates gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extra-gonadal tissues may vary several fold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion (provided by RefSeq, Jul 2008).

Rabbit anti Human inhibin beta B antibody detects a band of 52 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Western Blotting
Anti inhibin beta B detects a band of approximately 52 kDa in human adipose tissue.
Product Form
Purified IgG - liquid
Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
KLH-conjugated synthetic peptide corresponding to aa 369-397 of human inhibin beta B
For research purposes only.
12 months from date of despatch.
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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Entrez Gene
GO Terms
GO:0001541 ovarian follicle development
GO:0006952 defense response
GO:0005576 extracellular region
GO:0005125 cytokine activity
GO:0005179 hormone activity
GO:0040007 growth
GO:0008083 growth factor activity
GO:0009267 cellular response to starvation
GO:0046881 positive regulation of follicle-stimulating hormone secretion
GO:0046882 negative regulation of follicle-stimulating hormone secretion
GO:0032869 cellular response to insulin stimulus
GO:0032924 activin receptor signaling pathway
GO:0046789 host cell surface receptor binding
GO:0042803 protein homodimerization activity
GO:0045444 fat cell differentiation
GO:0046676 negative regulation of insulin secretion
GO:0048178 negative regulation of hepatocyte growth factor biosynthetic process
GO:0048471 perinuclear region of cytoplasm
GO:0060279 positive regulation of ovulation



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