IL-17D antibody

Rabbit anti Human INTERLEUKIN-17D:Preservative Free

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
IL-17D

Product Code Applications Pack Size List Price Your Price Qty
AHP2838Z
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E WB 0.1 mg loader
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loader
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Rabbit anti Human interleukin-17D antibody, recognizes interleukin-17D (IL-17D), also known as IL-27.

IL-17D is a member of the IL-17 family of cytokines. The receptor of 17-D has yet to be identified, although there have been some reports that it is able to interact with the receptor IL-17RA. There is also limited information regarding the biological functions elicited by IL-17D, however it is believed to stimulate the production of other cytokines including IL-6, IL-8 and GM-CSF. IL-17D may also play a role in local immune responses through induction of myeloid growth factors, chemokines, stimulatory local infiltration and proliferation of leukocytes (Liu et al. 2020).

Target Species
Human
Product Form
Purified IgG - lyophilized
Reconstitution
Reconstitute with 0.1 ml distilled water
Antiserum Preparation
Produced from sera of rabbits immunized with recombinant human interleukin-17D and purified by affinity chromatography
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
None present
Carrier Free
Yes
Immunogen
E. coli derived recombinant human interleukin-17D
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml after reconstitution
Endotoxin Level
< 0.1 ng/μg of protein (< 1 EU/μg)
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Prior to reconstitution store at -20°C.
After reconstitution store at -20°C.

This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 0.5 ug/ml 2.0 ug/ml
Western Blotting 0.1 ug/ml 0.2 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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UniProt
Q8TAD2
Entrez Gene
IL17D
GO Terms
GO:0005125 cytokine activity
GO:0005615 extracellular space
GO:0006954 inflammatory response
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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