GSK3 Beta (pTyr216) antibody


Filter by Application:
WB P ResetRabbit anti GSK3 Beta (pTyr216)
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- GSK3 Beta (pTyr216)
Rabbit anti GSK3 Beta (pTyr216) antibody recognizes GSK3 beta when phosphorylated at tyrosine 216. GSK3 is a member of the CMGC family of kinases. GSK3 comprises two isoforms, alpha and beta, with 85% total homology and 98% homology between kinase domains. GSK3 beta is phosphorylated at tyrosine 216 via autophosphorylation, Fyn and PYK2. Phosphorylation of GSK3 beta at tyrosine 216 activates GSK3 alpha leading to phosphorylation of downstream targets such as the insulin receptor and glucose-6-phosphate. |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Expected from Sequence Rat Expected from Sequence - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to GSK3 BETA (pTyr216) was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
50% Glycerol - Immunogen
- Phospho specific-peptide corresponding to residues surrounding tyrosine 216 of human GSK3 beta
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Immunohistology - Paraffin | ![]() |
1/50 | 1/100 |
Western Blotting | ![]() |
1/500 | 1/2000 |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Goat anti Rabbit IgG (Fc):Biotin | ||||||
Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Goat anti Rabbit IgG (Fc):FITC | ||||||
Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Goat anti Rabbit IgG (Fc):HRP | ||||||
Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Sheep anti Rabbit IgG:FITC | ||||||
Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Sheep anti Rabbit IgG:RPE |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB* | 0.5 ml | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | TidyBlot Western Blot Detection Reagent:HRP |
- UniProt
- P49841
- Entrez Gene
- GSK3B
- GO Terms
- GO:0001085 RNA polymerase II transcription factor binding
- GO:0001837 epithelial to mesenchymal transition
- GO:0001954 positive regulation of cell-matrix adhesion
- GO:0002039 p53 binding
- GO:0005829 cytosol
- GO:0004674 protein serine/threonine kinase activity
- GO:0005524 ATP binding
- GO:0005634 nucleus
- GO:0005977 glycogen metabolic process
- View More GO Terms
- GO:0006983 ER overload response
- GO:0007411 axon guidance
- GO:0008013 beta-catenin binding
- GO:0018105 peptidyl-serine phosphorylation
- GO:0048015 phosphatidylinositol-mediated signaling
- GO:0021766 hippocampus development
- GO:0030877 beta-catenin destruction complex
- GO:0031333 negative regulation of protein complex assembly
- GO:0031334 positive regulation of protein complex assembly
- GO:0031625 ubiquitin protein ligase binding
- GO:0032091 negative regulation of protein binding
- GO:0032855 positive regulation of Rac GTPase activity
- GO:0034236 protein kinase A catalytic subunit binding
- GO:0034747 Axin-APC-beta-catenin-GSK3B complex
- GO:0043066 negative regulation of apoptosis
- GO:0045732 positive regulation of protein catabolic process
- GO:0046827 positive regulation of protein export from nucleus
- GO:0048011 nerve growth factor receptor signaling pathway
- GO:0050321 tau-protein kinase activity
- GO:0051059 NF-kappaB binding
- GO:0060070 canonical Wnt receptor signaling pathway
- GO:0071109 superior temporal gyrus development
AHP2627


If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
View all Anti-Human ProductsAlways be the first to know.
When we launch new products and resources to help you achieve more in the lab.
Yes, sign me up