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GSK3 Alpha antibody

Rabbit anti GSK3 Alpha

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
GSK3 Alpha

Product Code Applications Pack Size List Price Your Price Qty
VPA00205
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 100 µl loader
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loader

Rabbit anti Human GSK3 alpha antibody recognizes glycogen synthase kinase-3 (GSK3) alpha, also known as serine/threonine-protein kinase GSK3A.

Encoded by the GSK3A gene, GSK3 alpha encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease (provided by RefSeq, Oct 2011).

Rabbit anti Human GSK3 alpha antibody detects a band of 51 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti GSK3 alpha detects a band of approximately 51 kDa in HEK293 cell lysates.
Product Form
Purified IgG - liquid
Preparation
Rabbit Ig fraction prepared by ammonium sulphate precipitation.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
Immunogen
KLH conjugated synthetic peptide between 76-105 amino acids from the N-terminal region of human GSK3 alpha
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml.
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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Synonyms
GSK3A
UniProt
P49840
Entrez Gene
GSK3A
GO Terms
GO:0005829 cytosol
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0006468 protein phosphorylation
GO:0008286 insulin receptor signaling pathway
GO:0010905 negative regulation of UDP-glucose catabolic process
GO:0048015 phosphatidylinositol-mediated signaling
GO:0030877 beta-catenin destruction complex
GO:0034236 protein kinase A catalytic subunit binding
GO:0045732 positive regulation of protein catabolic process
GO:0046325 negative regulation of glucose import
GO:0046627 negative regulation of insulin receptor signaling pathway
GO:0048011 nerve growth factor receptor signaling pathway
GO:0050321 tau-protein kinase activity
GO:0051348 negative regulation of transferase activity

VPA00205

151204

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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