GITRL antibody

Rabbit anti Human GITRL:Preservative Free

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
GITRL

Product Code Applications Pack Size List Price Your Price Qty
AHP2805Z
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E WB 0.1 mg loader
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loader
Search for Batch Specific Datasheets

Rabbit anti Human GITRL antibody recognizes Glucocorticoid-Induced TNF-Related Ligand (GITRL) also known as activation-inducible TNR-related ligand and TNFSF18.

GITRL is expressed in many components of the innate and adaptive immune system, but is mainly expressed on antigen presenting cells (Nocentini et al. 2007).

GITRL is a ligand of the receptor GITR, upon binding of its ligand, GITR is activated and plays a role in autoimmune/inflammatory processes and regulates leukocyte extravasation (Krausz et al. 2007, Nocentini et al. 2007).

Target Species
Human
Product Form
Purified IgG - lyophilized
Reconstitution
Reconstitute with 0.1 ml distilled water
Antiserum Preparation
Produced from sera of rabbits immunized with recombinant human AITRL and purified by affinity chromatography
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
None present
Carrier Free
Yes
Immunogen
E. coli derived recombinant human GITRL
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml after reconstitution
Endotoxin Level
< 0.1 ng/μg of protein (< 1 EU/μg)
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Prior to reconstitution store at -20°C.
After reconstitution store at -20°C.

This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 0.5 ug/ml 2.0 ug/ml
Western Blotting 0.1 ug/ml 0.2 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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Synonyms
TNFSF18
UniProt
Q9UNG2
Entrez Gene
TNFSF18
GO Terms
GO:0016021 integral to membrane
GO:0007165 signal transduction
GO:0005125 cytokine activity
GO:0005164 tumor necrosis factor receptor binding
GO:0005615 extracellular space
GO:0006916 anti-apoptosis
GO:0006955 immune response
GO:0007267 cell-cell signaling
View more products with GITRL specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Human Products