Galectin-1 antibody

Rabbit anti Galectin-1

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
Galectin-1

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VPA00080
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SDS Safety Datasheet SDS
WB 100 µl loader
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Rabbit anti Human galectin-1 antibody recognizes human galectin-1 (gal-1) also known lactose-binding lectin 1. Gal-1 is a member of the galectin family of beta-galactoside-binding proteins, which exhibits both intracellular and extracellular functions and is differentially expressed by a wide range of normal and neoplastic tissues.

Gal-1 has been implicated in several major cellular functions including proliferation, motility, hematopoietic cell differentiation, apoptosis promotion and immunoregulatory effects. The expression of gal-1 by neuronal and glial cells correlates with neuroregeneration following injury, and show the importance of gal-1 to primary sensory neurons and synaptic connections in the spinal cord, during embryonic development.

Rabbit anti Human galectin-1 antibody detects gal-1 as a single band of 13 kDa in a range of human cell line lysates. Cross reactivity with rodent cell lines is also observed.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Rabbit anti galectin-1 detects a band of approximately 13 kDa in K562 cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
Immunogen
E.coli derived recombinant human galectin-1.
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
P09382
Entrez Gene
LGALS1
GO Terms
GO:0016936 galactoside binding
GO:0006915 apoptosis
GO:0004871 signal transducer activity
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0042981 regulation of apoptosis
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade
View more products with GALECTIN specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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