Galectin-1 antibody

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Rabbit anti Galectin-1

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Product Code Applications Pack Size List Price Quantity
VPA00080
Datasheet
WB
MSDS
100 µl loader

Rabbit anti Human galectin-1 antibody recognizes human galectin-1 (gal-1) also known lactose-binding lectin 1. Gal-1 is a member of the galectin family of beta-galactoside-binding proteins, which exhibits both intracellular and extracellular functions and is differentially expressed by a wide range of normal and neoplastic tissues.

Gal-1 has been implicated in several major cellular functions including proliferation, motility, hematopoietic cell differentiation, apoptosis promotion and immunoregulatory effects. The expression of gal-1 by neuronal and glial cells correlates with neuroregeneration following injury, and studies have shown the importance of gal-1 to primary sensory neurons and synaptic connections in the spinal cord, during embryonic development.

Rabbit anti Human galectin-1 antibody detects gal-1 as a single band of 13 kDa in a range of human cell line lysates. Cross reactivity with rodent cell lines is also observed.

Product Details

Target Species
Human
Western Blotting
Rabbit anti galectin-1 detects a band of approximately 13 kDa in K562 cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
E.coli derived recombinant human galectin-1.

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
Guarantee
As supplied, 12 months from date of despatch.

More Information

UniProt
P09382
Entrez Gene
LGALS1
GO Terms
GO:0016936 galactoside binding
GO:0006915 apoptosis
GO:0004871 signal transducer activity
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0042981 regulation of apoptosis
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory
For research purposes only

Applications of Galectin-1 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P WB 2 ml