Galectin-1 antibody
Rabbit anti Human galectin-1 antibody recognizes human galectin-1 (gal-1) also known lactose-binding lectin 1. Gal-1 is a member of the galectin family of beta-galactoside-binding proteins, which exhibits both intracellular and extracellular functions and is differentially expressed by a wide range of normal and neoplastic tissues.
Gal-1 has been implicated in several major cellular functions including proliferation, motility, hematopoietic cell differentiation, apoptosis promotion and immunoregulatory effects. The expression of gal-1 by neuronal and glial cells correlates with neuroregeneration following injury, and studies have shown the importance of gal-1 to primary sensory neurons and synaptic connections in the spinal cord, during embryonic development.
Rabbit anti Human galectin-1 antibody detects gal-1 as a single band of 13 kDa in a range of human cell line lysates. Cross reactivity with rodent cell lines is also observed.
Gal-1 has been implicated in several major cellular functions including proliferation, motility, hematopoietic cell differentiation, apoptosis promotion and immunoregulatory effects. The expression of gal-1 by neuronal and glial cells correlates with neuroregeneration following injury, and studies have shown the importance of gal-1 to primary sensory neurons and synaptic connections in the spinal cord, during embryonic development.
Rabbit anti Human galectin-1 antibody detects gal-1 as a single band of 13 kDa in a range of human cell line lysates. Cross reactivity with rodent cell lines is also observed.
Product Details
- Target Species
- Human
- Western Blotting
- Rabbit anti galectin-1 detects a band of approximately 13 kDa in K562 cell lysates.
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- E.coli derived recombinant human galectin-1.
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Guarantee
- As supplied, 12 months from date of despatch.
More Information
- UniProt
- P09382
- Entrez Gene
- LGALS1
- GO Terms
- GO:0016936 galactoside binding
- GO:0006915 apoptosis
- GO:0004871 signal transducer activity
- GO:0005578 proteinaceous extracellular matrix
- GO:0005615 extracellular space
- GO:0005737 cytoplasm
- GO:0042981 regulation of apoptosis
- GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of Galectin-1 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml |
