Fatty Acid Synthase antibody

Rabbit anti Fatty Acid Synthase

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
Fatty Acid Synthase

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VPA00266
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Rabbit anti Human fatty acid synthase antibody recognizes fatty acid synthase, also known as FASN, FAS and short chain dehydrogenase/reductase family 27X, member 1.

The enzyme encoded by the fatty acid synthase gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha (provided by RefSeq, Jul 2008).

Rabbit anti Human fatty acid synthase antibody detects a band of 273 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti fatty acid synthase detects a band of approximately 273 kDa in Raji cell lysates.
Product Form
Ig fraction - liquid
Preparation
Rabbit Ig fraction prepared by ammonium sulphate precipitation.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
Immunogen
KLH-conjugated synthetic peptide corresponding to aa 942-973 of human fatty acid synthase
Approx. Protein Concentrations
Ig concentration 0.5 mg/ml.
Regulatory
For research purposes only
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
P49327
Entrez Gene
FASN
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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