Erythropoietin Receptor antibody
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WB ResetRabbit anti Erythropoietin Receptor
- Product Type
- PrecisionAb Polyclonal
- Isotype
- Polyclonal IgG
- Format
- Purified
- Specificity
- Erythropoietin Receptor
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| Rabbit anti Human erythropoietin receptor antibody recognizes the erythropoietin receptor also known as EPO-R and EPOR. The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates JAK2 tyrosine kinase which activates different intracellular pathways including Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of the erythropoietin receptor may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants (provided by RefSeq, May 2010). Rabbit anti Human erythropoietin receptor antibody detects a band of 55 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
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- Target Species
- Human
- Western Blotting
- Anti erythropoietin receptor detects a band of approximately 55 kDa in K562 cell lysate.
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline.
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3).
- Immunogen
- KLH-conjugated synthetic peptide corresponding to aa 470-504 of human erythropoietin receptor
- Regulatory
- For research purposes only.
- Guarantee
- 12 months from date of despatch.
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
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| Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml | Log in | |||
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| Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
- UniProt
- P19235
- Entrez Gene
- EPOR
- GO Terms
- GO:0005576 extracellular region
- GO:0004900 erythropoietin receptor activity
- GO:0005887 integral to plasma membrane
View more products with ERYTHROPOIETIN specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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