DR3 antibody

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WB ResetRabbit anti Human DR3 (N-Terminal)
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- DR3
- Region
- (N-TERMINAL)
Rabbit anti Human DR3 antibody recognises a ~59 kDa apoptosis related protein designated DR3 (death receptor-3). DR3 is a cell surface receptor with a death domain, with functional similarities to TNFR1 and Fas (CD95). The ligand for DR3 has very recently been identified and has been termed Apo-3L. DR3 itself has also been called Wsl-1, Apo-3, TRAMP and LARD, and functionally induces apoptosis and NF-κB activation. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antisera to DR3 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.02% Sodium Azide - Immunogen
- Peptide sequence QGGTRSPRCDCAGDFH from amino terminus of human DR3
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Western Blotting | ![]() |
1/500 | 1/1000 |
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Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg | Log in | |||
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Description | Goat anti Rabbit IgG (Fc):Biotin | ||||||
Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg | Log in | |||
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Description | Goat anti Rabbit IgG (Fc):FITC | ||||||
Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg | Log in | |||
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Description | Goat anti Rabbit IgG (Fc):HRP | ||||||
Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg | Log in | |||
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Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg | Log in | |||
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Description | Sheep anti Rabbit IgG:FITC | ||||||
Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml | Log in | |||
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Description | Sheep anti Rabbit IgG:RPE |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
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TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB* | 0.5 ml | Log in | |||
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Description | TidyBlot Western Blot Detection Reagent:HRP |
Further Reading
-
Chinnaiyan, A.M. et al. (1996) Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95.
Science. 274 (5289): 990-2. -
Marsters, S.A. et al. (1998) Identification of a ligand for the death-domain-containing receptor Apo3.
Curr Biol. 8 (9): 525-8.
AHP435

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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