CXCL6 antibody

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Rabbit anti Human CXCL6:Preservative Free

Product Type: Polyclonal Antibody
Isotype: Polyclonal IgG
Specificity: CXCL6

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AHP2794Z Datasheet Datasheet SDS SDS	E WB	0.1 mg		Log in	Get Quote
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Mouse anti Human CXCL6 antibody, recognizes C-X-C motif chemokine 6 (CXCL6) also known as chemokine alpha 3, granulocyte chemotactic protein 2 and small inducible cytokine B6.

CXCL6 is a member of the ELR⁺ CXC family of chemokines. It is a potent pro-inflammatory neutrophil chemoattractant which can elicit ultrastructural changes and activate pathways that define neutrophil phenotype and function (Mittal et al. 2008, Linge et al. 2008). It achieves this through the regulation of downstream pathways via its receptors CXCR1 and CXCR2 (Lui et al. 2019).

Target Species: Human
Product Form: Purified IgG - lyophilized
Reconstitution: Reconstitute with 0.1 ml distilled water
Antiserum Preparation: Produced from sera of rabbits immunized with recombinant human CXCL6 and purified by affinity chromatography
Buffer Solution: Phosphate buffered saline
Preservative Stabilisers: None present
Carrier Free: Yes
Immunogen: E. coli derived full length recombinant human CXCL6
Approx. Protein Concentrations: IgG concentration 1.0 mg/ml after reconstitution
Endotoxin Level: < 0.1 ng/μg of protein (< 1 EU/μg)
Regulatory: For research purposes only
Guarantee: 12 months from date of despatch

Prior to reconstitution store at -20°C.
After reconstitution store at -20°C.

This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
ELISA		0.5 ug/ml	2.0 ug/ml
Western Blotting		0.1 ug/ml	0.2 ug/ml

Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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Synonyms: GCP-2
UniProt: P80162
Entrez Gene: CXCL6
GO Terms: GO:0007165 signal transduction; GO:0005615 extracellular space; GO:0006935 chemotaxis; GO:0006954 inflammatory response; GO:0006955 immune response; GO:0007267 cell-cell signaling; GO:0008009 chemokine activity; GO:0008201 heparin binding