CXCL6 antibody
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Mouse anti Human CXCL6 antibody, recognizes C-X-C motif chemokine 6 (CXCL6) also known as chemokine alpha 3, granulocyte chemotactic protein 2 and small inducible cytokine B6.
CXCL6 is a member of the ELR+ CXC family of chemokines. It is a potent pro-inflammatory neutrophil chemoattractant which can elicit ultrastructural changes and activate pathways that define neutrophil phenotype and function (Mittal et al. 2008, Linge et al. 2008). It achieves this through the regulation of downstream pathways via its receptors CXCR1 and CXCR2 (Lui et al. 2019).
CXCL6 is a member of the ELR+ CXC family of chemokines. It is a potent pro-inflammatory neutrophil chemoattractant which can elicit ultrastructural changes and activate pathways that define neutrophil phenotype and function (Mittal et al. 2008, Linge et al. 2008). It achieves this through the regulation of downstream pathways via its receptors CXCR1 and CXCR2 (Lui et al. 2019).
Product Details
- Target Species
- Human
- Product Form
- Purified IgG - lyophilized
- Reconstitution
- Reconstitute with 0.1 ml distilled water
- Antiserum Preparation
- Produced from sera of rabbits immunized with recombinant human CXCL6 and purified by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present
- Carrier Free
- Yes
- Immunogen
- E. coli derived full length recombinant human CXCL6
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml after reconstitution
- Endotoxin Level
- < 0.1 ng/μg of protein (< 1 EU/μg)
Storage Information
- Storage
- Prior to reconstitution store at -20°C.
After reconstitution store at -20°C.
This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P80162
- Entrez Gene
- CXCL6
- GO Terms
- GO:0007165 signal transduction
- GO:0005615 extracellular space
- GO:0006935 chemotaxis
- GO:0006954 inflammatory response
- GO:0006955 immune response
- GO:0007267 cell-cell signaling
- GO:0008009 chemokine activity
- GO:0008201 heparin binding
- Regulatory
- For research purposes only
Applications of CXCL6 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA | 0.5 ug/ml | 2.0 ug/ml | |
| Western Blotting | 0.1 ug/ml | 0.2 ug/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
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| Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
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| Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
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| Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
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| Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
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| Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
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| Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
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| Sheep anti Rabbit IgG:DyLight®488 | STAR36D488GA | F IF WB | 0.1 mg | ||
| Sheep anti Rabbit IgG:DyLight®680 | STAR36D680GA | F IF WB | 0.1 mg | ||
| Sheep anti Rabbit IgG:Dylight®800 | STAR36D800GA | F IF WB | 0.1 mg |
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