CXCL13 antibody
Rabbit anti Human CXCL13
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- CXCL13
Rabbit anti Human CXCL13 antibody recognizes human BCA-1 (B cell attractant chemokine), a 10.1 kDa CXC cytokine designated CXCL13, a potent chemoattractant for B lymphocytes expressed at high levels in the liver and to a lesser extent by lymph nodes, spleen, stomach, appendix and salivary glands. BCA-1 functions as a ligand for Burkitt's lymphoma receptor 1 (BLR-1), a chemokine receptor designated CXCR5, expressed by all mature B lymphocytes. |
- Target Species
- Human
- Product Form
- Purified IgG - lyophilized
- Reconstitution
- Reconstitute with 0.1ml distilled water.
For long term storage the addition of 0.09% sodium azide is recommended. - Antiserum Preparation
- Antisera to human CXCL13 were raised by repeated immunizations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present.
- Carrier Free
- Yes
- Immunogen
- Recombinant human CXCL13.
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml after reconstitution
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
After reconstitution store at -20°C.
This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | 0.5ug/ml | ||
Western Blotting | 0.1 | 0.2ug/ml |
- ELISA
- This purified human CXCL13 antibody may be used in an indirect ELISA or as the capture reagent in a sandwich ELISA with biotinylated human CXCL13 antibody (AHP766B) as the detection reagent.
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References for CXCL13 antibody
-
Gunn, M.D. et al. (1998) A B-cell-homing chemokine made in lymphoid follicles activates Burkitt’s lymphoma receptor-1.
Nature. 391: 799-803.
- RRID
- AB_2088329
- UniProt
- O43927
- Entrez Gene
- CXCL13
- GO Terms
- GO:0005615 extracellular space
- GO:0005625 soluble fraction
- GO:0006935 chemotaxis
- GO:0006954 inflammatory response
- GO:0006955 immune response
- GO:0007204 elevation of cytosolic calcium ion concentration
- GO:0007267 cell-cell signaling
- GO:0008009 chemokine activity
AHP766
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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