CD256 antibody
Rabbit anti Human CD256 antibody recognizes Tumor necrosis factor ligand superfamily member 13, also known as CD256, A proliferation-inducing ligand, APRIL, TNF- and APOL-related leukocyte expressed ligand 2 or TNF-related death ligand 1.
CD256 is a member of the tumour necrosis factor family, expressed in B cells and several tumour cells. The protein is involved in stimulating B and T cell proliferation, triggering humoral immune responses, activating NF-kappaB and inducing cell death. CD256 is thought to play a role in autoimmune diseases and cancer.
CD256 is a member of the tumour necrosis factor family, expressed in B cells and several tumour cells. The protein is involved in stimulating B and T cell proliferation, triggering humoral immune responses, activating NF-kappaB and inducing cell death. CD256 is thought to play a role in autoimmune diseases and cancer.
Product Details
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Rat Mouse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antisera to human CD256 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.02% Sodium Azide - Immunogen
- Synthetic peptide corresponding to amino acids 196 to 210 of human CD256.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 18 months from date of despatch.
More Information
- UniProt
- O75888
- Entrez Gene
- TNFSF13
- GO Terms
- GO:0016020 membrane
- GO:0007165 signal transduction
- GO:0005125 cytokine activity
- GO:0005164 tumor necrosis factor receptor binding
- GO:0005615 extracellular space
- GO:0005654 nucleoplasm
- GO:0006955 immune response
- GO:0008284 positive regulation of cell proliferation
- GO:0016071 mRNA metabolic process
- GO:0048298 positive regulation of isotype switching to IgA isotypes
- Regulatory
- For research purposes only
Applications of CD256 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunohistology - Paraffin | 1/100 | ||
| Western Blotting | 1/250 | 1/1000 |
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
- Western Blotting
- AHP953 detects a band approximately 27kD in Jurkat cell lysates
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