Sheep anti Aldosterone antibody recognizes aldosterone, a steroid hormone (mineralocorticoid family) produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland to regulate the bodies electrolyte and water balance. It is synthesized from cholesterol by aldosterone synthase, which is absent in other sections of the adrenal gland. It acts directly on the kidney to decrease the rate of sodium-ion excretion (with accompanying retention of water), and to increase the rate of potassium-ion excretion.Sheep anti Aldosterone antibody exhibits negligible reactivity with a range of associated hormones and derivatives.
- Target Species
- Product Form
- Ig fraction - liquid
- Ig fraction prepared by ammonium sulphate precipitation
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide (NaN3)
- Aldosterone conjugated to Bovine Serum Albumin.
- Approx. Protein Concentrations
- 5.0 mg/ml
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- Shelf Life
- 18 months from date of despatch.
- For research purposes only
Applications of Aldosterone antibody
|Application Name||Verified||Min Dilution||Max Dilution|
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
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Product Specific References
References for Aldosterone antibody
Cronshaw, J. et al. (1989) Pre-natal development of the adrenal gland in the mallard duck (Anas platyrhynchos).
Cell Tissue Res. 258 (3): 593-601.