Sheep anti Aldosterone antibody recognizes aldosterone, a steroid hormone (mineralocorticoid family) produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland to regulate the bodies electrolyte and water balance. It is synthesized from cholesterol by aldosterone synthase, which is absent in other sections of the adrenal gland.
It acts directly on the kidney to decrease the rate of sodium-ion excretion (with accompanying retention of water), and to increase the rate of potassium-ion excretion.Sheep anti Aldosterone antibody exhibits negligible reactivity with a range of associated hormones and derivatives.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- Aldosterone conjugated to Bovine Serum Albumin.
- Approx. Protein Concentrations
- 5.0 mg/ml
- Store at -20°C only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Aldosterone antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
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Secondary Antibodies Available
Product Specific References
References for Aldosterone antibody
Cronshaw, J. et al. (1989) Pre-natal development of the adrenal gland in the mallard duck (Anas platyrhynchos).
Cell Tissue Res. 258 (3): 593-601.