Acetaminophen antibody

Sheep anti Acetaminophen

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
Acetaminophen

Product Code Applications Pack Size List Price Your Price Qty
0016-0104
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
IY P 0.5 ml
List Price Your Price
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Sheep anti acetaminophen antibody recognizes acetaminophen, a commonly used analgesic and antipyretic.

Sheep anti acetaminophen antibody is suitable for use in polarization fluoroimmunoassays (Coxon et al. 1988). Sheep anti acetaminophen antibody has also been used successfully for the demonstration of bound acetaminophen adducts in the liver of mice by immunohistochemistry on formalin fixed, paraffin embedded tissue sections (Scheiermann et al. 2013).

Target Species
Chemical
Product Form
Serum - liquid
Preservative Stabilisers
<0.1% Sodium Azide (NaN3)
Immunogen
P-Aminophenol hemisuccinide conjugated to Keyhole Limpet Hemocyanin.
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunoassay
Immunohistology - Paraffin
Western Blotting
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

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References for Acetaminophen antibody

  1. Gallacher, G. et al. (1988) Design of the immunogen and label for use in a fluoroimmunoassay for paracetamol.
    Ann Clin Biochem. 25: 42-48.
  2. Coxon, R. et al. (1988) Development of a specific polarisation fluoroimmunoassay for paracetamol in serum.
    Ann Clin Biochem. 25: 49-52
  3. Scheiermann, P. et al. (2013) Application of Interleukin-22 Mediates Protection in Experimental Acetaminophen-Induced Acute Liver Injury.
    Am J Pathol. pii: S0002-9440(13)00019-9.
  4. Cernat, A. et al. (2015) Nanostructured Platform Based on Graphene-Polypyrrole Composite for Immunosensor Fabrication
    Int. J. Electrochem. Sci., 10 (2015) 4718 - 31

Synonyms
Paracetamol
RRID
AB_619644
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