Feline Leukaemia Virus gp70 antibody | C11D8
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Mouse anti Feline Leukemia Virus gp70 antibody, clone C11D8 recognizes the gp85/gp70 envelope glycoprotein of feline leukemia virus. The antibody specifically recognizes the epitope defined by amino acids 214-218 of the gp70 sequence (aa MGPNL).
Some weak cross-reactivity with the sequence MGPLL found in the FeLV p15e membrane protein may also occur.
This antibody effectively neutralizes all three FeLV subgroups (A,B and C).
Removal of the preservative is recommended prior to use in functional assays - Bio-Rad recommend the use of a Slide-A-Lyser® dialysis cassette for this purpose.
Some weak cross-reactivity with the sequence MGPLL found in the FeLV p15e membrane protein may also occur.
This antibody effectively neutralizes all three FeLV subgroups (A,B and C).
Removal of the preservative is recommended prior to use in functional assays - Bio-Rad recommend the use of a Slide-A-Lyser® dialysis cassette for this purpose.
Product Details
- Target Species
- Viral
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.05% Sodium Azide - Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- Q85525
- Regulatory
- For research purposes only
Applications of Feline Leukaemia Virus gp70 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry | |||
| Immunohistology - Frozen | |||
| Immunohistology - Paraffin | |||
| Immunoprecipitation | |||
| Western Blotting |
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Rabbit F(ab')2 anti Mouse IgG:HRP (Human Adsorbed) | STAR13B | C E P RE WB | 1 mg |
|
Product Specific References
References for Feline Leukaemia Virus gp70 antibody
-
Grant, C.K. et al. (1983) Feline leukemia virus envelope gp70 of subgroups B and C defined by monoclonal antibodies with cytotoxic and neutralizing functions.
J Immunol. 131 (6): 3042-8. -
Buchmann, A.U. et al. (2010) Does a Feline Leukemia Virus Infection Pave the Way for Bartonella henselae Infection in Cats?
J Clin Microbiol. 48: 3295-300. -
Rolim, V.M. et al. (2016) Myocarditis caused by Feline Immunodeficiency Virus in Five Cats with Hypertrophic Cardiomyopathy.
J Comp Pathol. 154 (1): 3-8. -
Cristo, T.G. et al. (2019) Feline Leukaemia Virus Associated with Leukaemia in Cats in Santa Catarina, Brazil.
J Comp Pathol. 170: 10-21.
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