Feline Leukaemia Virus gp70 antibody | C11D8

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Mouse anti Feline Leukaemia Virus gp70

Product Type
Monoclonal Antibody
Clone
C11D8
Isotype
IgG2b
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
MCA1897 C F IP P WB 0.25 mg
Mouse anti Feline Leukaemia Virus gp70 antibody, clone C11D8 recognizes the gp85/gp70 envelope glycoprotein of feline leukaemia virus. The antibody specifically recognises the epitope defined by amino acids 214-218 of the gp70 sequence (aa MGPNL).

Some weak cross-reactivity with the sequence MGPLL found in the FeLV p15e membrane protein may also occur.

This antibody effectively neutralises all three FeLV subgroups (A,B and C).

Removal of the preservative is recommended prior to use in functional assays - Bio-Rad recommend the use of a Slide-A-Lyser® dialysis cassette for this purpose.

Product Details

Target Species
Viral
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.05%Sodium Azide
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml

Storage Information

Storage
Store at +4oC or at -20oC if preferred.

This product should be stored undiluted.

Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch.

More Information

UniProt
Q85525 Related reagents
Regulatory
For research purposes only

Applications of Feline Leukaemia Virus gp70 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Flow Cytometry
Immunohistology - Frozen
Immunohistology - Paraffin
Immunoprecipitation
Western Blotting
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Rabbit F(ab')2 anti Mouse IgG:HRP (Human Adsorbed) STAR13B 1 mg C E P RE WB

Product Specific References

References for Feline Leukaemia Virus gp70 antibody

  1. Grant, C.K. et al. (1983) Feline leukemia virus envelope gp70 of subgroups B and C defined by monoclonal antibodies with cytotoxic and neutralizing functions.
    J Immunol. 131 (6): 3042-8.
  2. Buchmann, A.U. et al. (2010) Does a Feline Leukemia Virus Infection Pave the Way for Bartonella henselae Infection in Cats?
    J Clin Microbiol. 48: 3295-300.
  3. Rolim, V.M. et al. (2016) Myocarditis caused by Feline Immunodeficiency Virus in Five Cats with Hypertrophic Cardiomyopathy.
    J Comp Pathol. 154 (1): 3-8.