Feline Leukaemia Virus gp70 antibody | C11D8
Mouse anti Feline Leukaemia Virus gp70
- Product Type
- Monoclonal Antibody
- Clone
- C11D8
- Isotype
- IgG2b
- Specificity
- Feline Leukaemia Virus gp70
Antibody Quality and Performance Guarantee
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| Mouse anti Feline Leukemia Virus gp70 antibody, clone C11D8 recognizes the gp85/gp70 envelope glycoprotein of feline leukemia virus. The antibody specifically recognizes the epitope defined by amino acids 214-218 of the gp70 sequence (aa MGPNL). Some weak cross-reactivity with the sequence MGPLL found in the FeLV p15e membrane protein may also occur. This antibody effectively neutralizes all three FeLV subgroups (A,B and C). Removal of the preservative is recommended prior to use in functional assays. |
- Target Species
- Viral
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% sodium azide (NaN3)
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry |  |
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| Immunohistology - Frozen | |
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| Immunohistology - Paraffin | |
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| Immunoprecipitation | |
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| Western Blotting | |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Rabbit F(ab')2 anti Mouse IgG:HRP (Human Adsorbed) | STAR13B | C E P RE WB | 1 mg |
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| List Price | Your Price | ||||||
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| Description | Rabbit F(ab')2 anti Mouse IgG:HRP (Human Adsorbed) | ||||||
References for Feline Leukaemia Virus gp70 antibody
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Grant, C.K. et al. (1983) Feline leukemia virus envelope gp70 of subgroups B and C defined by monoclonal antibodies with cytotoxic and neutralizing functions.
J Immunol. 131 (6): 3042-8. -
Buchmann, A.U. et al. (2010) Does a Feline Leukemia Virus Infection Pave the Way for Bartonella henselae Infection in Cats?
J Clin Microbiol. 48: 3295-300. -
Rolim, V.M. et al. (2016) Myocarditis caused by Feline Immunodeficiency Virus in Five Cats with Hypertrophic Cardiomyopathy.
J Comp Pathol. 154 (1): 3-8. -
Cristo, T.G. et al. (2019) Feline Leukaemia Virus Associated with Leukaemia in Cats in Santa Catarina, Brazil.
J Comp Pathol. 170: 10-21. -
Biezus, G. et al. (2020) Plasma Cell Pododermatitis Associated With Feline Leukemia Virus (FeLV) and Concomitant Feline Immunodeficiency Virus (FIV) Infection in a Cat.
Top Companion Anim Med. 41: 100475. -
Gómez, Á. et al. (2023) Feline osteochondromatosis in a 12-year-old feline leukaemia virus-negative cat.
J Comp Pathol. 205: 24-6. -
Wronski, J.G. et al. (2023) Ophthalmic and immunopathological characterization of systemic infectious diseases in cats.
Vet Pathol. 60 (3): 352-359. -
Pandolfo, G.W. et al. (2024) Neoplastic and non-neoplastic diseases associated with feline leukaemia virus (FeLV) in cats in southern Brazil.
Comp Immunol Microbiol Infect Dis. 112: 102228.
View The Latest Product References
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de Cristo, T.G. et al. (2024) Immunocytochemistry of bone marrow aspirates: a tool in the diagnosis of feline leukemia virus infection in cats.
J Comp Pathol. 214: 12-18. -
Pandolfo, G.W. et al. (2024) Unusual mediastinal abscess to Pseudomonas aeruginosa in a cat in southern Brazil
Braz J Vet Pathol, 2025, vol. 18, e018004
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