CD90 antibody | T11D7e
Mouse anti Rat CD90
- Product Type
- Monoclonal Antibody
- Clone
- T11D7e
- Isotype
- IgM
- Specificity
- CD90
Mouse anti Rat CD90 antibody, clone T11D7e recognizes mouse and rat CD90 also known as Thy1.1. Thy1.1 is a monomorphic determinant in rat but polymorphic in mice. Clone T11D7e reacts with Thy1.1 mice e.g. AKR and FVB mice, but not Thy1.2 mice such as CBA and BALB/c. Clone T11D7e is useful for removal of T lymphocytes from cell populations by complement mediated cytotoxicity (Lake et al. 1979). Mouse anti Rat CD90 antibody, clone T11D7e is routinely tested in flow cytometry using mouse thymocytes. |
- Target Species
- Rat
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Ig fraction - liquid
- Preparation
- Ig fraction prepared by ammonium sulphate precipitation from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide - Immunogen
- Xenogeneic rat thymocytes.
- Approx. Protein Concentrations
- IgM concentration 1 mg/ml
- Fusion Partners
- Spleen cells from immunized CBA mice were fused with cells of the mouse NS1 myeloma cell line.
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Cytotoxic Assays | |||
Flow Cytometry | 1/5 |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
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Goat anti Mouse IgM:Alk. Phos.(Human Adsorbed) | STAR138A | C E P WB | 1 ml | Log in | |||
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Description | Goat anti Mouse IgM:Alk. Phos.(Human Adsorbed) | ||||||
Goat anti Mouse IgG/A/M:HRP (Human Adsorbed) | STAR87P | E | 1 mg | Log in | |||
List Price | Your Price | ||||||
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Description | Goat anti Mouse IgG/A/M:HRP (Human Adsorbed) |
References for CD90 antibody
-
Lake, P. et al. (1979) Production and characterization of cytotoxic Thy-1 antibody-secreting hybrid cell lines. Detection of T cell subsets.
Eur J Immunol. 9 (11): 875-86. -
Yasumizu, R. et al. (1988) Development of donor-derived thymic lymphomas after allogeneic bone marrow transplantation in AKR/J mice.
J Immunol. 141 (6): 2181-6. -
Fabian, R.H. (1990) Uptake of antineuronal IgM by CNS neurons: comparison with antineuronal IgG.
Neurology. 40 (3 Pt 1): 419-22. -
Ogasawara, K. et al. (1990) Ia restriction specificity of KLH-specific T cells from allogeneic bone marrow chimeras is influenced by histocompatibility at the H-2 and minor histocompatibility loci.
Microbiol Immunol. 34 (12): 1025-39. -
Mahanthappa, N.K. et al. (1996) Glial growth factor 2, a soluble neuregulin, directly increases Schwann cell motility and indirectly promotes neurite outgrowth.
J Neurosci. 16: 4673-83. -
Simitzi, C. et al. (2015) Data in support on the shape of Schwann cells and sympathetic neurons onto microconically structured silicon surfaces.
Data Brief. 4: 636-40. -
Pasten, C. et al. (2015) ApoER2 and Reelin are expressed in regenerating peripheral nerve and regulate Schwann cell migration by activating the Rac1 GEF protein, Tiam1.
Mol Cell Neurosci. 69: 1-11. -
Deliyanti, D. & Wilkinson-Berka, J.L. (2015) Inhibition of NOX1/4 with GKT137831: a potential novel treatment to attenuate neuroglial cell inflammation in the retina.
J Neuroinflammation. 12: 136.
View The Latest Product References
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Heinen, A. et al. (2015) Fingolimod induces the transition to a nerve regeneration promoting Schwann cell phenotype.
Exp Neurol. 271: 25-35. -
Dietrich, N. et al. (2016) The DPP4 Inhibitor Linagliptin Protects from Experimental Diabetic Retinopathy.
PLoS One. 11 (12): e0167853. -
Ee, X. et al. (2017) Transgenic SCs expressing GDNF-IRES-DsRed impair nerve regeneration within acellular nerve allografts.
Biotechnol Bioeng. 114 (9): 2121-30. -
Wang, J. et al. (2020) CTCF-mediated chromatin looping in EGR2 regulation and SUZ12 recruitment critical for peripheral myelination and repair.
Nat Commun. 11 (1): 4133. -
Warren, P.M. et al. (2020) Secretion of a mammalian chondroitinase ABC aids glial integration at PNS/CNS boundaries.
Sci Rep. 10 (1): 11262. -
Piovesana, R. et al. (2020) Muscarinic receptors modulate Nerve Growth Factor production in rat Schwann-like adipose-derived stem cells and in Schwann cells.
Sci Rep. 10 (1): 7159. -
Castelnovo, L.F. et al. (2020) Membrane Progesterone Receptors (mPRs/PAQRs) Differently Regulate Migration, Proliferation, and Differentiation in Rat Schwann Cells.
J Mol Neurosci. 70 (3): 433-48. -
Ma, S. et al. (2021) Effect of papaverine on axonal outgrowth of primary retinal ganglion cells of Sprague Dawley rats.
Exp Eye Res. 212: 108797. -
Salazar Intriago, M.S. et al. (2021) The Mechanisms Mediated by α7 Acetylcholine Nicotinic Receptors May Contribute to Peripheral Nerve Regeneration.
Molecules.26(24):7668. -
Uezumi, A. et al. (2021) Mesenchymal Bmp3b expression maintains skeletal muscle integrity and decreases in age-related sarcopenia.
J Clin Invest. 131 (1): e139617. -
De Vitis, E. et al. (2021) A microfabricated multi-compartment device for neuron and Schwann cell differentiation.
Sci Rep. 11 (1): 7019. -
Botticelli, E. et al. (2022) Analysis of Signal Transduction Pathways Downstream M2 Receptor Activation: Effects on Schwann Cell Migration and Morphology
Life. 12 (2): 211. -
Piovesana, R. et al. (2022) Notch Signal Mediates the Cross-Interaction between M2 Muscarinic Acetylcholine Receptor and Neuregulin/ErbB Pathway: Effects on Schwann Cell Proliferation.
Biomolecules. 12 (2): 239. -
Huang, J.H. et al. (2022) Schwann cells-derived exosomes promote functional recovery after spinal cord injury by promoting angiogenesis.
Front Cell Neurosci. 16: 1077071. -
Numata-Uematasu, Y. et al. (2023) In vitro myelination using explant culture of dorsal root ganglia: An efficient tool for analyzing peripheral nerve differentiation and disease modeling.
PLoS One. 18 (5): e0285897. -
Botticelli, E. et al. (2023) α7 Nicotinic Acetylcholine Receptors May Improve Schwann Cell Regenerating Potential via Metabotropic Signaling Pathways.
Cells.12 (11): 1494.
- Synonyms
- THY1
- THY1.1
- RRID
- AB_322809
- UniProt
- P01830
- Entrez Gene
- Thy1
- GO Terms
- GO:0001525 angiogenesis
- GO:0007010 cytoskeleton organization
- GO:0005829 cytosol
- GO:0005100 Rho GTPase activator activity
- GO:0006469 negative regulation of protein kinase activity
- GO:0016337 cell-cell adhesion
- GO:0019901 protein kinase binding
- GO:0030336 negative regulation of cell migration
- GO:0030426 growth cone
- View More GO Terms
- GO:0034235 GPI anchor binding
- GO:0043066 negative regulation of apoptosis
- GO:0043547 positive regulation of GTPase activity
- GO:0045576 mast cell activation
- GO:0046549 retinal cone cell development
- GO:0048041 focal adhesion assembly
- GO:0048147 negative regulation of fibroblast proliferation
- GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
- GO:0050771 negative regulation of axonogenesis
- GO:0050852 T cell receptor signaling pathway
- GO:0050860 negative regulation of T cell receptor signaling pathway
- GO:0050870 positive regulation of T cell activation
- GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
MCA04GT
160810 1702MCA04G
158823 1608If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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