Mouse anti Pig CD31 antibody, clone LCI-9
recognizes porcine Platelet endothelial cell adhesion molecule, also known as CD31 or PECAM-1. Porcine CD31 is a 740 amino acid ~140 kDa single pass type 1 transmembrane glycoprotein bearing six Ig-like C2-type
domains. CD31 is expressed by various cell types, but particularly by endothelial cells where it is required for leukocyte transendothelial migration (UniProt:Q95242
Mouse anti Pig CD31 antibody, clone LCI-9 has been used successfully for recognition of porcine CD31 by flow cytometry (Peterson et al. 2005
) and immunofluorescence microscopy (Nasu et al. 1999
- Target Species
- Product Form
- Tissue Culture Supernatant - liquid
- Preservative Stabilisers
- Porcine CD31/human IgGFc fusion protein.
- Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
- 18 months from date of despatch.
- Entrez Gene
- GO Terms
integral to membrane
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of CD31 antibody
|Immunohistology - Frozen
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
Copyright © 2020 Bio-Rad Antibodies (formerly AbD Serotec)
Secondary Antibodies Available
Negative Isotype Controls Available
Application Based External Images
Immunohistology - Frozen
Product Specific References
References for CD31 antibody
Peterson, M.D. et al. (2005) Monocyte adhesion to xenogeneic endothelium during laminar flow is dependent on alpha-Gal-mediated monocyte activation.
J Immunol. 174 (12): 8072-81.
Nasu, K. et al. (1999) Alpha-galactosyl-mediated activation of porcine endothelial cells: studies on CD31 and VE-cadherin in adhesion and signaling.
Transplantation. 1999 Sep 27;68(6): 861-7.
Peterson, M.D. et al. (2005) Monocyte-induced endothelial calcium signaling mediates early xenogeneic endothelial activation.
Am J Transplant. 5: 237-47.
Harrower, T.P. et al. (2006) Long-term survival and integration of porcine expanded neural precursor cell grafts in a rat model of Parkinson's disease.
Exp Neurol. 197: 56-69.
Al-Shalmani, S. et al. (2011) Quercetin and its principal metabolites, but not myricetin, oppose lipopolysaccharide-induced hyporesponsiveness of the porcine isolated coronary artery.
Br J Pharmacol. 162: 1485-97.
Piriou-Guzylack, L. (2008) Membrane markers of the immune cells in swine: an update.
Vet Res. 39: 54.