CD31 antibody | LCI-9
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Mouse anti Pig CD31
- Product Type
- Monoclonal Antibody
- Clone
- LCI-9
- Isotype
- IgM
- Specificity
- CD31
Antibody Quality and Performance Guarantee
| Mouse anti Pig CD31 antibody, clone LCI-9 recognizes porcine Platelet endothelial cell adhesion molecule, also known as CD31 or PECAM-1. Porcine CD31 is a 740 amino acid ~140 kDa single pass type 1 transmembrane glycoprotein bearing six Ig-like C2-type domains. CD31 is expressed by various cell types, but particularly by endothelial cells where it is required for leukocyte transendothelial migration (UniProt:Q95242). Mouse anti Pig CD31 antibody, clone LCI-9 has been used successfully for recognition of porcine CD31 by flow cytometry (Peterson et al. 2005) and immunofluorescence microscopy (Nasu et al. 1999). |
- Target Species
- Pig
- Product Form
- Tissue culture supernatant - liquid
- Preservative Stabilisers
- 0.09% sodium azide (NaN3)
- Immunogen
- Porcine CD31/human IgGFc fusion protein.
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry |  |
||
| Immunohistology - Frozen | |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Mouse IgM:Alk. Phos.(Human Adsorbed) | STAR138A | C E P WB | 1 ml |
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| Description | Goat anti Mouse IgM:Alk. Phos.(Human Adsorbed) | ||||||
| Goat anti Mouse IgG/A/M:Alk. Phos. | STAR87A | C E WB | 1 mg |
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| Description | Goat anti Mouse IgG/A/M:Alk. Phos. | ||||||
| Goat anti Mouse IgG/A/M:HRP (Human Adsorbed) | STAR87P | E | 1 mg |
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| Description | Goat anti Mouse IgG/A/M:HRP (Human Adsorbed) | ||||||
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse IgM Negative Control | MCA692 | F | 100 Tests |
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| Description | Mouse IgM Negative Control | ||||||
References for CD31 antibody
-
Peterson, M.D. et al. (2005) Monocyte adhesion to xenogeneic endothelium during laminar flow is dependent on alpha-Gal-mediated monocyte activation.
J Immunol. 174 (12): 8072-81. -
Nasu, K. et al. (1999) Alpha-galactosyl-mediated activation of porcine endothelial cells: studies on CD31 and VE-cadherin in adhesion and signaling.
Transplantation. 1999 Sep 27;68(6): 861-7. -
Peterson, M.D. et al. (2005) Monocyte-induced endothelial calcium signaling mediates early xenogeneic endothelial activation.
Am J Transplant. 5: 237-47. -
Harrower, T.P. et al. (2006) Long-term survival and integration of porcine expanded neural precursor cell grafts in a rat model of Parkinson's disease.
Exp Neurol. 197: 56-69. -
Al-Shalmani, S. et al. (2011) Quercetin and its principal metabolites, but not myricetin, oppose lipopolysaccharide-induced hyporesponsiveness of the porcine isolated coronary artery.
Br J Pharmacol. 162: 1485-97.
Further Reading
-
Piriou-Guzylack, L. (2008) Membrane markers of the immune cells in swine: an update.
Vet Res. 39: 54.
- Synonyms
- PECAM-1
- RRID
- AB_2236793
- UniProt
- Q95242
- Entrez Gene
- PECAM1
- GO Terms
- GO:0007155 cell adhesion
- GO:0016021 integral to membrane
- GO:0030054 cell junction
MCA1747
149029
1705
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