SSB antibody | OTI1E11

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Mouse anti SSB

Product Type
PrecisionAb Monoclonal
Clone
OTI1E11
Isotype
IgG2a
Format
Purified
Product Code Applications Pack Size List Price Quantity
VMA00112
Datasheet
WB
MSDS
100 µl loader

Mouse anti Human SSB antibody recognizes SSB, also known as La ribonucleoprotein domain family, member 3, SS-B/La protein, autoantigen La, la autoantigen, lupus La antigen, lupus La protein or sjoegren syndrome type B antigen.

The protein encoded by the SSB gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus (provided by RefSeq, Nov 2011).

Mouse anti Human SSB antibody detects a band of 50 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Anti SSB detects a band of approximately 50 kDa in HEK293 cell lysates.
Product Form
Purified IgG - liquid
Preparation
Mouse monoclonal antibody purified by affinity chromatography from ascites
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
50% Glycerol
Immunogen
Full-length protein expressed in 293T cell transfected with human SSB expression vector

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
Guarantee
As supplied, 12 months from date of despatch.

More Information

UniProt
P05455 Related reagents
Entrez Gene
SSB Related reagents
GO Terms
GO:0000049 tRNA binding
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0003729 mRNA binding
GO:0030529 ribonucleoprotein complex
GO:0005634 nucleus
GO:0006400 tRNA modification
GO:0008334 histone mRNA metabolic process
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory
For research purposes only

Applications of SSB antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml

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