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Prostate Specific Antigen antibody | RM323

Rabbit anti Prostate Specific Antigen

Product Type
Monoclonal Antibody
Clone
RM323
Isotype
IgG
Specificity
Prostate Specific Antigen

Product Code Applications Pack Size List Price Your Price Qty
MCA6349
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E P WB * 0.1 ml loader
List Price Your Price
loader

Rabbit anti prostate specific antigen antibody recognizes prostate-specific antigen, also known as PSA, seminin, and KLK3.

Prostate specific antigen is a serine protease that functions in liquefaction of seminal fluid and remains localized to the prostate, withy less than 1% released to circulation (Cetinkaya et al. 2010). Prostate specific antigen is produced by normal and cancerous prostate cells, and is not produced in significant quantities in any other tissue in men. Prostate specific antigen can be a diagnostic indicator for prostate cancer, and can be used to detect recurrence after local therapies and to follow response to systemic therapies for metastatic disease (LeBeau et al. 2010). Accordingly, prostate specific antigen testing has increased the number of men diagnosed with and treated for prostate cancer. However, the value of systematic screening with regard to mortality is uncertain (Tikkinen et al. 2018).

Target Species
Human
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein A from animal origin-free culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
1% Bovine Serum Albumin
50% Glycerol
Immunogen
Native prostate specific antigen protein purified from human seminal fluid
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20°C only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1/1000 1/5000
Immunohistology - Paraffin 1/500 1/1000
Western Blotting 1 1/1000 1/2500
  1. 1Use non-reduced conditions
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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UniProt
P07288
Entrez Gene
KLK3
GO Terms
GO:0004252 serine-type endopeptidase activity
GO:0005576 extracellular region
GO:0006508 proteolysis
GO:0016525 negative regulation of angiogenesis

MCA6349

157611

If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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