Rabbit anti prostate specific antigen antibody
recognizes prostate-specific antigen, also known as PSA, seminin, and KLK3.
Prostate specific antigen is a serine protease that functions in liquefaction of seminal fluid and remains localized to the prostate, withy less than 1% released to circulation (Cetinkaya et al. 2010
). Prostate specific antigen is produced by normal and cancerous prostate cells, and is not produced in significant quantities in any other tissue in men. Prostate specific antigen can be a diagnostic indicator for prostate cancer, and can be used to detect recurrence after local therapies and to follow response to systemic therapies for metastatic disease (LeBeau et al. 2010
). Accordingly, prostate specific antigen testing has increased the number of men diagnosed with and treated for prostate cancer. However, the value of systematic screening with regard to mortality is uncertain (Tikkinen et al. 2018
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A from animal origin-free culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
1% Bovine Serum Albumin
- Native prostate specific antigen protein purified from human seminal fluid
- Store at -20°C only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
serine-type endopeptidase activity
negative regulation of angiogenesis
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Prostate Specific Antigen antibody
|Immunohistology - Paraffin
|Western Blotting 1
- 1Use non-reduced conditions
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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Secondary Antibodies Available
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