PPP5C antibody | OTI5G5

Mouse anti PPP5C

Product Type
PrecisionAb Monoclonal
Clone
OTI5G5
Isotype
IgG1
Format
Purified
Specificity
PPP5C

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VMA00365
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Mouse anti Human PPP5C antibody, clone OTI5G5 recognizes PPP5C, also known as serine/threonine-protein phosphatase 5 and protein phosphatase T (PPT).

The PPP5C gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues, many of which are involved in the regulation of cell growth and differentiation. The product of the PPP5C gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants (provided by RefSeq, Feb 2011).

Mouse anti Human PPP5C antibody detects a band of 58 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti PPP5C detects a band of approximately 58 kDa in HeLa cell lysates.
Product Form
Purified IgG - liquid
Preparation
Mouse monoclonal antibody purified by affinity chromatography from ascites.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
50% Glycerol
Immunogen
Full length recombinant human PPP5C (NP_006238) produced in HEK293T cells
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml.
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml loader
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Description Goat anti Mouse IgG (H/L):HRP

UniProt
P53041
Entrez Gene
PPP5C
GO Terms
GO:0004722 protein serine/threonine phosphatase activity
GO:0004871 signal transducer activity
GO:0046872 metal ion binding
GO:0005634 nucleus
GO:0005794 Golgi apparatus
GO:0006350 transcription
GO:0006470 protein dephosphorylation
GO:0007067 mitosis
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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