p63 antibody | RM383

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Rabbit anti p63

Product Type
Monoclonal Antibody
Clone
RM383
Isotype
IgG
Product Code Applications Pack Size List Price Quantity
MCA6332
Datasheet
P WB
SDS
0.1 ml loader

Rabbit anti Human p63 antibody recognizes tumor protein 63, also known as CUSP, KET, P63, P73H, P73L, TP73L. p63 is a transcription factor and important regulator of cell proliferation and survival. This protein plays a major role in maintenance and differentiation of stem cells, and is involved with epidermal development, heart development, and maintenance of female germ cells (Gonfloni et al. 2015). p63 is involved with tumorigenesis, and is commonly linked with epithelial malignancies including squamous cancers (Galoczova et al. 2018). Although p53, a close relative of 63, is frequently mutated in tumors, p53 is rarely mutated or deleted in cancer. Conflicting roles for p63 in cancer have been reported, with some studies showing oncogenic potential and other showing that p63 can function as a tumor suppressor (Inoue and Fry 2014).

Product Details

Target Species
Human
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography of Protein A from animal origin-free culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
1% Bovine Serum Albumin
50% Glycerol
Immunogen
A peptide corresponding to the area surrounding the C-terminus of Human p63

Storage Information

Storage
Store at -20°C only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use
Guarantee
12 months from date of despatch

More Information

UniProt
Q9H3D4
Entrez Gene
TP63
Regulatory
For research purposes only

Applications of p63 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 1/100 1/200
Western Blotting 1/500 1/1000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (Fc):Biotin STAR121B E WB 1 mg loader
Goat anti Rabbit IgG (Fc):FITC STAR121F F 1 mg loader
Goat anti Rabbit IgG (Fc):HRP STAR121P E WB 1 mg loader
Sheep anti Rabbit IgG:FITC STAR34B C F 1 mg loader
Sheep anti Rabbit IgG:DyLight®488 STAR36D488GA F IF WB 0.1 mg
Sheep anti Rabbit IgG:DyLight®680 STAR36D680GA F IF WB 0.1 mg
Sheep anti Rabbit IgG:Dylight®800 STAR36D800GA F IF WB 0.1 mg
Goat anti Rabbit IgG (H/L):HRP STAR124P C E WB 1 mg loader
Sheep anti Rabbit IgG:RPE STAR35A F 1 ml loader

Fluorescent Spectraviewer

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  • Select combined or multi-laser view to visualize the spectra