NAPSIN-A antibody | RM366

Rabbit anti NAPSIN-A

Product Type
Monoclonal Antibody
Clone
RM366
Isotype
IgG
Specificity
NAPSIN-A

Product Code Applications Pack Size List Price Your Price Qty
MCA6352
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
P WB 0.1 ml loader
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Rabbit anti napsin-A antibody recognizes napsin-A, also known as NAPSA and ASP4.

Napsin-A is an aspartic protease which is mainly expressed in alveolar type II cells of the lung, but is also expressed in normal kidney tissue (Yamashita et al. 2014). It is involved with maturation of surfactant proteins (Rekhtman et al. 2018). Because of the high expression of napsin-A in most primary lung adenocarcinomas and lack of expression in squamous cell carcinoma and other adenocarcinomas, the protein is a useful marker of tumour type (Uchida et al. 2017). Accordingly, immunohistochemistry (IHC) for napsin-A has been widely used as a sensitive diagnostic tool for lung adenocarcinoma (Zhu et al. 2015).

Target Species
Human
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein A from animal origin-free culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
1% Bovine Serum Albumin
50% Glycerol
Immunogen
A peptide corresponding to the N-terminus of human napsin-A
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20°C only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 1/500 1/2000
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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UniProt
O96009
Entrez Gene
NAPSA
GO Terms
GO:0004190 aspartic-type endopeptidase activity
GO:0005576 extracellular region
GO:0006508 proteolysis
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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