Rabbit anti napsin-A antibody
recognizes napsin-A, also known as NAPSA and ASP4.
Napsin-A is an aspartic protease which is mainly expressed in alveolar type II cells of the lung, but is also expressed in normal kidney tissue (Yamashita et al. 2014
). It is involved with maturation of surfactant proteins (Rekhtman et al. 2018
). Because of the high expression of napsin-A in most primary lung adenocarcinomas and lack of expression in squamous cell carcinoma and other adenocarcinomas, the protein is a useful marker of tumour type (Uchida et al. 2017
). Accordingly, immunohistochemistry (IHC) for napsin-A has been widely used as a sensitive diagnostic tool for lung adenocarcinoma (Zhu et al. 2015
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A from animal origin-free culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
1% Bovine Serum Albumin
- A peptide corresponding to the N-terminus of human napsin-A
- Store at -20°C only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
aspartic-type endopeptidase activity
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of NAPSIN-A antibody
|Immunohistology - Paraffin
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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Secondary Antibodies Available
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