MAP4K1 antibody | C01/4C3
IP-MS Validated
Mouse anti Human MAP4K1
- Product Type
- PrecisionAb Monoclonal
- Clone
- C01/4C3
- Isotype
- IgG1
- Format
- Purified
- Specificity
- MAP4K1
Antibody Quality and Performance Guarantee
| Mouse anti Human MAP4K1 antibody recognizes mitogen-activated protein kinase kinase kinase kinase 1, also known as hematopoietic progenitor kinase 1 (HPK1). MAP4K1 has been shown to play a role in the activation of c-Jun N-terminal kinases (JNKs) (Chuang et al. 2016) and IKK-alpha/beta. MAP4K1 supports apoptosis of T cells through inhibition of the anti-apoptotic action of NF-κB and induction of activity of JNK and OHPK1 (Schulze-Luehrmann et al. 2016). |
|
- Target Species
- Human
- Western Blotting
- Mouse anti Human MAP4K1 antibody detects a band of 96 kDa in Jurkat cell lysates
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- E. coli-derived recombinant protein, aa 1-274 of human MAP4K1
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunoprecipitation |  |
2.5 µg | |
| Western Blotting | |
1/2000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
- UniProt
- Q92918
- Entrez Gene
- MAP4K1
- GO Terms
- GO:0000185 activation of MAPKKK activity
- GO:0005515 protein binding
- GO:0005083 small GTPase regulator activity
- GO:0005524 ATP binding
- GO:0007257 activation of JUN kinase activity
- GO:0008349 MAP kinase kinase kinase kinase activity
- GO:0018105 peptidyl-serine phosphorylation
VMA00990
100006569
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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