Lysosome Membrane Protein 2 antibody

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Anti Lysosome Membrane Protein 2 Antibody (PrecisionAb Monoclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with Mouse anti Human lysosome membrane protein 2 antibody (**VMA00074**) followed by detection with HRP conjugated Goat anti Mouse IgG (1/10,000, STAR207P) and visualized on the ChemiDoc MP with 300 second exposure. Arrow points to lysosome membrane protein 2 (molecular weight 80 kDa).

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Mouse anti Lysosome Membrane Protein 2

Product Type: PrecisionAb Monoclonal
Isotype: IgG2b
Format: Purified
Specificity: Lysosome Membrane Protein 2

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Product Code Applications Pack Size List Price Your Price Qty

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VMA00074 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
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Mouse anti Human lysosome membrane protein 2 antibody recognizes lysosome membrane protein 2, also known as 85 kDa lysosomal membrane sialoglycoprotein, LGP85, CD36 antigen-like 2, SCARB2, LIMP II and scavenger receptor class B member 2.

Lysosome membrane protein 2 is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. This protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Human LIMP2 is a ubiquitously expressed protein involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in lysosome membrane protein 2 caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for SCARB2 (provided by RefSeq, Feb 2011).

Mouse anti Human lysosome membrane protein 2 antibody detects a band of 80 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Anti lysosome membrane protein 2 detects a band of approximately 80 kDa in LNCaP cell lysates.
Product Form: Purified IgG - liquid
Preparation: Mouse monoclonal antibody purified by affinity chromatography on Protein G from tissue culture supernatant.
Buffer Solution: Phosphate buffered saline.
Preservative Stabilisers: 0.09% Sodium Azide (NaN₃).
Immunogen: E. Coli derived recombinant protein, aa249-478 of human lysosome membrane protein 2
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Mouse IgG (H/L):HRP	STAR207P	WB	2 ml	Log in	Get Quote
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Description	Goat anti Mouse IgG (H/L):HRP

UniProt: Q14108
Entrez Gene: SCARB2
GO Terms: GO:0005515 protein binding; GO:0007155 cell adhesion; GO:0004872 receptor activity; GO:0005887 integral to plasma membrane; GO:0005624 membrane fraction; GO:0005765 lysosomal membrane