IRF6 antibody | OTI2C10

Mouse anti IRF6

Product Type
PrecisionAb Monoclonal
Clone
OTI2C10
Isotype
IgG1
Format
Purified
Specificity
IRF6

Product Code Applications Pack Size List Price Your Price Qty
VMA00187
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 100 µl loader
List Price Your Price
loader
Search for Batch Specific Datasheets

Mouse anti Human IRF6 antibody, clone OTI2C10 recognizes interferon regulatory factor 6 (IRF6).

Encoded by the IRF6 gene, interferon regulatory factor 6 is member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. IRF6 may be a transcriptional activator. Mutations in the IRF6 gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in IRF6 are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants (provided by RefSeq, May 2011).

Mouse anti Human IRF6 antibody, clone OTI2C10 detects a band of 58 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti IRF6 detects a band of approximately 58 kDa in HEK293 cell lysates.
Product Form
Purified IgG - liquid
Preparation
Mouse monoclonal antibody purified by affinity chromatography from ascites.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
50% Glycerol
Immunogen
Full length recombinant human IRF6 (NP_006138) produced in HEK293T cells
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml.
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description Product Code Applications Pack Size List Price Your Price Quantity
Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml loader
List Price Your Price
loader
Description Goat anti Mouse IgG (H/L):HRP

UniProt
O14896
Entrez Gene
IRF6
GO Terms
GO:0005515 protein binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-dependent
GO:0007050 cell cycle arrest
GO:0008285 negative regulation of cell proliferation
GO:0045941 positive regulation of transcription
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0060337 type I interferon-mediated signaling pathway
GO:0060644 mammary gland epithelial cell differentiation
Request a different product with this specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Human Products