IGFBP-7 antibody

Mouse anti IGFBP-7

Product Type
PrecisionAb Monoclonal
Isotype
IgG1
Format
Purified
Specificity
IGFBP-7

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VMA00078
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Mouse anti Human IGFBP-7 antibody recognizes Insulin-like growth factor-binding protein 7 , also known as IBP-7, IGF-binding protein 7, IGFBP-rP1, MAC25 protein, PGI2-stimulating factor, prostacyclin-stimulating factor and tumor-derived adhesion factor (TAF).

IGFBP-7 encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for IGFBP-7, and one variant has been associated with retinal arterial macroaneurysm.

Mouse anti Human IGFBP-7 antibody detects a band of 31 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti IGFBP-7 detects a band of approximately 31 kDa in HeLa cell lysates.
Product Form
Purified IgG - liquid
Preparation
Mouse monoclonal antibody purified by affinity chromatography on Protein G from tissue culture supernatant.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
Immunogen
E. Coli derived recombinant protein, aa52-156 of human IGFBP-7
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml loader
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Description Goat anti Mouse IgG (H/L):HRP

UniProt
Q16270
Entrez Gene
IGFBP7
GO Terms
GO:0001558 regulation of cell growth
GO:0007155 cell adhesion
GO:0005520 insulin-like growth factor binding
GO:0005615 extracellular space
GO:0008285 negative regulation of cell proliferation
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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