IGF2BP-2 antibody | OTI3C8

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Anti IGF2BP-2 Antibody, clone OTI3C8 (PrecisionAb™ Monoclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with IGF2BP-2 antibody followed by detection with HRP conjugated Goat anti Mouse IgG (1/10,000, STAR207P) and visualized on the ChemiDoc MP with 4 second exposure. Arrow points to IGF2BP-2 (molecular weight 62 & 66 kDa)

Mouse anti IGF2BP-2

Mouse anti human IGF2BP-2 antibody recognizes insulin-like growth factor 2 mRNA-binding protein 2, also known as IGF2 binding protein 2 or VICKZ family member 2. This antibody has been extensively validated for western blotting using whole cell lysates.

Product Type: PrecisionAb™ Monoclonal
Clone: OTI3C8
Isotype: IgG1
Format: Purified

Product Code	Applications	Pack Size	Your Price	List Price	Quantity
VMA00401 Datasheet	WB MSDS	100 µl	Log in		Get Quote

Summary
Secondary Antibodies

Mouse anti Human IGF2BP-2 antibody recognizes insulin-like growth factor 2 mRNA-binding protein 2 (IGFBP-2), also known as IGF2 binding protein 2 and VICKZ family member 2.

IGF2BP-2 is a member of the IGF-II mRNA-binding protein (IMP) family. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized (provided by RefSeq, Jul 2008).

Mouse anti IGF2BP-2 antibody detects bands of 62 and 66 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species: Human
Western Blotting: Anti IGF2BP-2 detects a bands of 62 and 66 kDa in HepG2 cell lysates
Product Form: Purified IgG - liquid
Preparation: Mouse monoclonal antibody purified by affinity chromatography from ascites
Buffer Solution: Phosphate buffered saline
Preservative Stabilisers: 0.09% Sodium Azide (NaN₃)
1% Bovine Serum Albumin
50% Glycerol
Immunogen: Full length recombinant human IGF2BP-2 (NP_006539) produced in HEK293T cells
Instructions For Use: Please refer to the PrecisionAb western blotting protocol. For additional information on secondary antibody dilution and exposure time see product web page.

Storage Information

Storage: Store undiluted at -20^oC, avoiding repeated freeze thaw cycles.
Guarantee: As supplied, 12 months from date of despatch.

More Information

UniProt: Q9Y6M1 Related reagents
Entrez Gene: IGF2BP2 Related reagents
GO Terms: GO:0000166 nucleotide binding; GO:0005515 protein binding; GO:0003730 mRNA 3'-UTR binding; GO:0005829 cytosol; GO:0005634 nucleus; GO:0009653 anatomical structure morphogenesis; GO:0017148 negative regulation of translation; GO:0042035 regulation of cytokine biosynthetic process; GO:0044430 cytoskeletal part; GO:0045182 translation regulator activity; GO:0048027 mRNA 5'-UTR binding
Acknowledgements: PrecisionAb™ is a trademark of Bio-Rad Laboratories.
Regulatory: For research purposes only

Applications of IGF2BP-2 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

PrecisionAb antibodies have been extensively validated for the western blot application. The antibody has been validated at the suggested dilution. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependant on sample type.

Secondary Antibodies Available

Description	Product Code	Applications	Pack Size	Your Price	List Price	Quantity
Goat anti Mouse IgG (H/L):HRP	STAR207P	WB	2 ml	Log in		Get Quote

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