IGF2BP-2 antibody | OTI3C8
Mouse anti Human IGF2BP-2 antibody recognizes insulin-like growth factor 2 mRNA-binding protein 2 (IGFBP-2), also known as IGF2 binding protein 2 and VICKZ family member 2.
IGF2BP-2 is a member of the IGF-II mRNA-binding protein (IMP) family. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized (provided by RefSeq, Jul 2008).
Mouse anti IGF2BP-2 antibody detects bands of 62 and 66 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
IGF2BP-2 is a member of the IGF-II mRNA-binding protein (IMP) family. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized (provided by RefSeq, Jul 2008).
Mouse anti IGF2BP-2 antibody detects bands of 62 and 66 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti IGF2BP-2 detects a bands of 62 and 66 kDa in HepG2 cell lysates
- Product Form
- Purified IgG - liquid
- Preparation
- Mouse monoclonal antibody purified by affinity chromatography from ascites
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
50% Glycerol - Immunogen
- Full length recombinant human IGF2BP-2 (NP_006539) produced in HEK293T cells
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Guarantee
- As supplied, 12 months from date of despatch.
More Information
- UniProt
- Q9Y6M1 Related reagents
- Entrez Gene
- IGF2BP2 Related reagents
- GO Terms
- GO:0000166 nucleotide binding
- GO:0005515 protein binding
- GO:0003730 mRNA 3'-UTR binding
- GO:0005829 cytosol
- GO:0005634 nucleus
- GO:0009653 anatomical structure morphogenesis
- GO:0017148 negative regulation of translation
- GO:0042035 regulation of cytokine biosynthetic process
- GO:0044430 cytoskeletal part
- GO:0045182 translation regulator activity
- GO:0048027 mRNA 5'-UTR binding
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of IGF2BP-2 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
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