IGF2BP-2 antibody | OTI3C8

Mouse anti IGF2BP-2

Product Type
PrecisionAb Monoclonal
Clone
OTI3C8
Isotype
IgG1
Format
Purified
Specificity
IGF2BP-2

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VMA00401
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WB 100 µl loader
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Mouse anti Human IGF2BP-2 antibody, clone OTI3C8 recognizes insulin-like growth factor 2 mRNA-binding protein 2 (IGFBP-2), also known as IGF2 binding protein 2 and VICKZ family member 2.

IGF2BP-2 is a member of the IGF-II mRNA-binding protein (IMP) family. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized (provided by RefSeq, Jul 2008).

Mouse anti IGF2BP-2 antibody, clone OTI3C8 detects bands of 62 and 66 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti IGF2BP-2 detects a bands of 62 and 66 kDa in HepG2 cell lysates.
Product Form
Purified IgG - liquid
Preparation
Mouse monoclonal antibody purified by affinity chromatography from ascites.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
50% Glycerol
Immunogen
Full length recombinant human IGF2BP-2 (NP_006539) produced in HEK293T cells
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml loader
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Description Goat anti Mouse IgG (H/L):HRP

UniProt
Q9Y6M1
Entrez Gene
IGF2BP2
GO Terms
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0003730 mRNA 3'-UTR binding
GO:0005829 cytosol
GO:0005634 nucleus
GO:0009653 anatomical structure morphogenesis
GO:0017148 negative regulation of translation
GO:0042035 regulation of cytokine biosynthetic process
GO:0044430 cytoskeletal part
GO:0045182 translation regulator activity
GO:0048027 mRNA 5'-UTR binding
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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