HbA1c antibody | AbD15785_IgG1
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E ResetHuman anti Human HbA1c
- Product Type
- Monoclonal Antibody
- Clone
- AbD15785_IgG1
- Isotype
- IgG1
- Specificity
- HbA1c
Human anti Human HbA1c antibody, clone AbD15785_IgG1 recognizes HbA1c, hemoglobin glycated at the N-terminal valine of the hemoglobin &beta chain. It does not bind to non-glycated hemoglobin. Besides binding to the normal glycated hemoglobin. Human anti Human HbA1c antibody, clone AbD15785_IgG1 also recognizes the glycated hemoglobin variants HbC, HbE, HbD and to a lesser degree HbS. Elevated HbF is not detected due to the absence of the hemoglobin β chain. The measurement of HbA1c levels is used to identify the average plasma glucose concentration. In diabetes mellitus, higher levels of HbA1c have been associated with cardiovascular disease and other diseases. Levels of more than 6.5% HbA1c (48 mmol/mol) are used as a criterion to diagnose diabetes. This antibody is also available in a Fab format (HCA180 ). |
- Target Species
- Human
- Product Form
- Human IgG1 antibody selected from the HuCAL phage display library and expressed in a human cell line.This antibody is supplied as a liquid.
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A
- Source
- HKB-11
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- The immunogens used in the generation of this antibody were:
A glycated peptide, corresponding to N-terminal 9 amino acids of haemoglobin beta chain coupled to the carrier proteins BSA and TRF
Purified HbA1c - Affinity
- The affinity of this antibody, as a monovalent fab against the immunogen is KD=28 nM as measured by real time, label-free molecular interaction analysis using HbA1c-BSA and HbA1c-TRF conjugates as immobilized antigen.
The affinity of this antibody, as a monovalent fab measured against purified HbA1c is KD=65 nM as measured by real time, label-free molecular interaction analysis using full length HbA1c as immobilized antigen. - Approx. Protein Concentrations
- Total protein concentration 0.5 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
- Acknowledgements
- This product and/or its use is covered by claims of U.S. patents, and/or pending U.S. and non-U.S. patent applications owned by or under license to Bio-Rad Laboratories, Inc. See bio-rad.com/en-us/trademarks for details.
- Licensed Use
- For in vitro research purposes only, unless otherwise specified in writing by Bio-Rad.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA |
- Technical Advice
- Recommended protocols and further information about HuCAL recombinant antibody technology can be found in the HuCAL Antibodies Technical Manual.
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Human anti Human HbA1c | HCA180 | E | 0.1 mg | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Human anti Human HbA1c | ||||||
Human anti Human HbA1c | HCA197 | E | 0.1 mg | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Human anti Human HbA1c | ||||||
Human anti Human HbA1c | HCA218 | E | 0.1 mg | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Human anti Human HbA1c |
HCA217
0213 0213R 160592If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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