GNB3 antibody | EF01/1A12
IP-MS Validated
Filter by Application:
WB ResetMouse anti GNB3
- Product Type
- PrecisionAb Monoclonal
- Clone
- EF01/1A12
- Isotype
- IgG1
- Format
- Purified
- Specificity
- GNB3
Antibody Quality and Performance Guarantee
| Mouse anti GNB3 antibody recognizes guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3, also known as transducin beta chain 3. GNB3 is the beta3 subunit of G-protein. G proteins transmit information from G-protein-coupled receptors at the plasma membrane to intracellular signaling pathways, regulating a variety of biochemical processes (Syrovatkina et al. 2016) including cell growth and mitosis (Wang and Zhang 2014). G-proteins, and also GNB3, appear to be associated with obesity. Duplication of the gene encoding GNB3 has been linked to an obesity phenotype in humans and in mice (Li et al. 2016). The C825T polymorphism (rs5443) of GNB3 has been associated with obesity, essential hypertension, atherosclerosis, coronary diseases, and cerebrovascular events with sex-specific effects (Gbadoe et al. 2016). |
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- Target Species
- Human
- Western Blotting
- Mouse anti GNB3 detects a band of approximately 32 kDa in mouse brain tissue lysates
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - Liquid
- Preparation
- Mouse monoclonal antibody affinity purified on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
- Immunogen
- E. coli-derived recombinant protein of amino acids 1-340 of human GNB3
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunoprecipitation |  |
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| Western Blotting | |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
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| List Price | Your Price | ||||||
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| Description | Goat anti Mouse IgG (H/L):HRP | ||||||
- UniProt
- P16520
- Entrez Gene
- GNB3
- GO Terms
- GO:0005886 plasma membrane
- GO:0003924 GTPase activity
- GO:0004871 signal transducer activity
- GO:0006112 energy reserve metabolic process
- GO:0007186 G-protein coupled receptor protein signaling pathway
- GO:0007268 synaptic transmission
- GO:0008217 regulation of blood pressure
- GO:0071377 cellular response to glucagon stimulus
VMA00948
100005802
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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