ELAVL1 antibody | 224CT6.5.3

Mouse anti ELAVL1

Product Type
PrecisionAb Monoclonal
Clone
224CT6.5.3
Isotype
IgG1
Format
Purified
Specificity
ELAVL1

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VMA00354
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Mouse anti Human ELAVL1 antibody recognizes ELAVL1, also known as ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R), ELAV-like protein 1, Hu antigen R, embryonic lethal and abnormal vision, drosophila, homolog-like 1, hu-antigen R.

The protein encoded by ELAVL1 gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. ELAVL1 has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy (provided by RefSeq, Sep 2012).

Mouse anti Human ELAVL1 antibody detects a band of 36 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti ELAVL1 detects a band of approximately 36 kDa in HEK293 cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Mouse monoclonal antibody purified by affinity chromatography on Protein G from tissue culture supernatant.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
Immunogen
Recombinant ELAVL1 protein
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml.
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml loader
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Description Goat anti Mouse IgG (H/L):HRP

UniProt
Q15717
Entrez Gene
ELAVL1
GO Terms
GO:0000166 nucleotide binding
GO:0003729 mRNA binding
GO:0005737 cytoplasm
GO:0005654 nucleoplasm
GO:0007275 multicellular organismal development
GO:0042802 identical protein binding
GO:0070935 3'-UTR-mediated mRNA stabilization
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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