EIF3H antibody | AB04/3F5
IP-MS Validated
Mouse anti EIF3H
- Product Type
- PrecisionAb Monoclonal
- Clone
- AB04/3F5
- Isotype
- IgG1
- Format
- Purified
- Specificity
- EIF3H
Antibody Quality and Performance Guarantee
| Mouse anti EIF3H antibody recognizes eukaryotic translation initiation factor 3 subunit H, also known as EIF3S3. EIF3H is a subunit of the mammalian EIF3 complex, and contributes to mRNA recruitment and ribosomal complex disassembly. EIF3H was found to be involved with regulation of cell growth and viability, which led to the suggestion that it could provide a growth advantage to cancer cells (Savinainen et al. 2006). Accordingly, it has been identified as a known driver of cell proliferation and survival in cancer, overexpressed in prostate, breast, and liver cancer, and has been associated with poor prognosis (Cappuzzo et al. 2009). EIF3H knockdown can lead to apoptosis of colorectal cancer cells, leading to its suggestion as a potential biomarker (Yu et al. 2018). |
|
- Target Species
- Human
- Western Blotting
- Mouse anti EIF3H detects a band of approximately 40 kDa in HeLa cell lysates
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - Liquid
- Preparation
- Mouse monoclonal antibody affinity purified on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
- Immunogen
- E. coli-derived recombinant protein of amino acids 1-352 of human EIF3H
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunoprecipitation |  |
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| Western Blotting | |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
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| List Price | Your Price | ||||||
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| Description | Goat anti Mouse IgG (H/L):HRP | ||||||
- UniProt
- O15372
- Entrez Gene
- EIF3H
- GO Terms
- GO:0005515 protein binding
- GO:0003743 translation initiation factor activity
- GO:0005829 cytosol
- GO:0005852 eukaryotic translation initiation factor 3 complex
- GO:0006446 regulation of translational initiation
VMA00935
100005654
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