EIF3G antibody | AB05/3H10
siRNA Validated
Mouse anti EIF3G
- Product Type
- PrecisionAb Monoclonal
- Clone
- AB05/3H10
- Isotype
- IgG1
- Format
- Purified
- Specificity
- EIF3G
Antibody Quality and Performance Guarantee
| Mouse anti EIF3G antibody recognizes eukaryotic translation initiation factor 3 subunit G, also known as EIF3S4. EIF3G is a subunit of the mammalian EIF3 complex, and is involved with translation reinitiation and protein synthesis (Kim et al. 2013). Roles for EIF3G have been identified in the cytoskeletal network (Burnicka-Turek et al. 2010) and in caspase-mediated apoptosis (Kim et al. 2013). EIF3G appears to play roles in cancer development, and clues have included its nuclear distribution in breast cancer cells (Zheng et al. 2016) and overexpression in an adriamycin-resistant erythroleukemia cell line (Zhu et al. 2009). It has also been suggested that EIF3G could be a target for managing chemoresistance in patients with colorectal cancer (Yang et al. 2018). A single nucleotide polymorphism is associated with risk of narcolepsy (Holm et al. 2015). |
|
- Target Species
- Human
- Western Blotting
- Mouse anti EIF3G detects a band of approximately 42 kDa in HEK293 cell lysates
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - Liquid
- Preparation
- Mouse monoclonal antibody affinity purified on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
- Immunogen
- E. coli-derived recombinant protein of amino acids 1-320 of human EIF3G
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
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| List Price | Your Price | ||||||
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| Description | Goat anti Mouse IgG (H/L):HRP | ||||||
- UniProt
- O75821
- Entrez Gene
- EIF3G
- GO Terms
- GO:0000166 nucleotide binding
- GO:0005515 protein binding
- GO:0003743 translation initiation factor activity
- GO:0005829 cytosol
- GO:0005634 nucleus
- GO:0005852 eukaryotic translation initiation factor 3 complex
- GO:0048471 perinuclear region of cytoplasm
VMA00934
100005651
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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